An improved in silico selection of phenotype affecting polymorphisms in SLC6A4, HTR1A and HTR2A genes

Objective Among the experimentally assessed DNA variations in serotonin related genes, some influence physiological expression of personality and mental disorders, others alter the responses to pharmacological and/or psychotherapeutic treatments. Because of the huge number of polymorphisms lying in...

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Veröffentlicht in:	Human psychopharmacology 2010-03, Vol.25 (2), p.153-161
Hauptverfasser:	Piva, Francesco, Giulietti, Matteo, Nardi, Bernardo, Bellantuono, Cesario, Principato, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	association Biotransformation - genetics computational biology Computational Biology - methods Databases, Genetic Expert Systems Genetic Association Studies Humans Mental Disorders - genetics MicroRNAs - genetics Phenotype Polymorphism, Genetic Polymorphism, Single Nucleotide Promoter Regions, Genetic Receptor, Serotonin, 5-HT1A - genetics Receptor, Serotonin, 5-HT2A - genetics RNA splicing RNA Splicing - genetics serotonin Serotonin - metabolism Serotonin Plasma Membrane Transport Proteins - genetics SNP Software
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