Mosaic vaccines elicit CD8 super(+) T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys

An effective HIV vaccine must elicit immune responses that recognize genetically diverse viruses. It must generate CD8 super(+) T lymphocytes that control HIV replication and CD4 super(+) T lymphocytes that provide help for the generation and maintenance of both cellular and humoral immune responses...

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Bibliographische Detailangaben

Veröffentlicht in:	Nature medicine 2010-03, Vol.16 (3), p.324-328
Hauptverfasser:	Santra, Sampa, Liao, Hua-Xin, Zhang, Ruijin, Muldoon, Mark, Watson, Sydeaka, Fischer, Will, Theiler, James, Szinger, James, Balachandran, Harikrishnan, Buzby, Adam, Quinn, David, Parks, Robert J, Tsao, Chun-Yen, Carville, Angela, Mansfield, Keith G, Pavlakis, George N, Felber, Barbara K, Haynes, Barton F, Korber, Bette T, Letvin, Norman L
Format:	Artikel
Sprache:	eng
Schlagworte:	Human immunodeficiency virus Macaca mulatta Vaccinia virus
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