Promoter methylation of the Wnt/b-catenin signaling antagonist Dkk-3 is associated with poor survival in gastric cancer

BACKGROUND: Abnormal activation of the Wnt/-catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene Dkk-3 in these cancers and its prognostic significance in gastric can...

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Veröffentlicht in:	Cancer 2009-01, Vol.115 (1), p.49-60
Hauptverfasser:	Yu, Jun, Tao, Qian, Cheng, Yuen Y, Lee, Kwan Y, Ng, Simon S M, Cheung, Kin F, Tian, Linwei, Rha, Sun Y, Neumann, Ulf, Rocken, Christoph, Ebert, Matthias P A, Chan, Francis K L, Sung, Joseph J Y
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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