Oxidative stress in systemic lupus erythematosus: Relationship to Th1 cytokine and disease activity

Abstract Imbalance between oxidative stress and helper T-cell (Th1)-derived cytokines is one possible cause for the pathogenesis of systemic lupus erythematosus (SLE). To evaluate the correlation between oxidative stress and Th1 cytokine level with the disease activity of SLE in the North Indian pop...

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Veröffentlicht in:	Immunology letters 2010-03, Vol.129 (1), p.7-12
Hauptverfasser:	Shah, Dilip, Kiran, Ravi, Wanchu, Ajay, Bhatnagar, Archana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergy and Immunology Catalase - metabolism Cell Extracts Cells, Cultured Disease Progression Erythematosus (SLE) Erythrocytes - enzymology Erythrocytes - immunology Erythrocytes - pathology Female Glutathione - metabolism Humans Interferon (IFN)-γ Interferon-gamma - genetics Interferon-gamma - metabolism Interleukin (IL)-12 Interleukin-12 - genetics Interleukin-12 - metabolism Lipid Peroxidation - immunology Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - metabolism Lupus Erythematosus, Systemic - physiopathology Male Malondialdehyde - metabolism Oxidative stress Oxidative Stress - immunology Superoxide Dismutase - metabolism Systemic lupus Th1 Cells - metabolism Th1 Cells - pathology
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