Results of eleven years' experience with heated perfusion for melanoma of the extremities
Eleven years have elapsed since we first added heat to regional perfusion for treatment of melanoma of the extremities. This report describes briefly our laboratory findings and our technique of hyperthermic perfusion and brings up to date the survival figures for the 165 patients (185 perfusions) w...
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Veröffentlicht in: | Cancer research (Chicago, Ill.) Ill.), 1979-06, Vol.39 (6 Pt 2), p.2255-2257 |
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creator | Stehlin, Jr, J S Giovanella, B C de Ipolyi, P D Anderson, R F |
description | Eleven years have elapsed since we first added heat to regional perfusion for treatment of melanoma of the extremities. This report describes briefly our laboratory findings and our technique of hyperthermic perfusion and brings up to date the survival figures for the 165 patients (185 perfusions) which were originally reported in 1975 (Stehlin et al., Surg. Gynecol. Obstet., 122: 3--14, 1966). A dramatic increase in the survival rate is documented for those patients with recurrent melanoma confined to the extremities. |
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This report describes briefly our laboratory findings and our technique of hyperthermic perfusion and brings up to date the survival figures for the 165 patients (185 perfusions) which were originally reported in 1975 (Stehlin et al., Surg. Gynecol. Obstet., 122: 3--14, 1966). A dramatic increase in the survival rate is documented for those patients with recurrent melanoma confined to the extremities.</description><identifier>ISSN: 0008-5472</identifier><identifier>PMID: 445425</identifier><language>eng</language><publisher>United States</publisher><subject>Chemotherapy, Cancer, Regional Perfusion ; Extremities ; Hot Temperature - adverse effects ; Hot Temperature - therapeutic use ; Humans ; Immunity ; Melanoma - immunology ; Melanoma - therapy ; Melphalan - administration & dosage ; Neoplasm Metastasis ; Recurrence ; Skin Neoplasms - immunology ; Skin Neoplasms - therapy</subject><ispartof>Cancer research (Chicago, Ill.), 1979-06, Vol.39 (6 Pt 2), p.2255-2257</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/445425$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stehlin, Jr, J S</creatorcontrib><creatorcontrib>Giovanella, B C</creatorcontrib><creatorcontrib>de Ipolyi, P D</creatorcontrib><creatorcontrib>Anderson, R F</creatorcontrib><title>Results of eleven years' experience with heated perfusion for melanoma of the extremities</title><title>Cancer research (Chicago, Ill.)</title><addtitle>Cancer Res</addtitle><description>Eleven years have elapsed since we first added heat to regional perfusion for treatment of melanoma of the extremities. This report describes briefly our laboratory findings and our technique of hyperthermic perfusion and brings up to date the survival figures for the 165 patients (185 perfusions) which were originally reported in 1975 (Stehlin et al., Surg. Gynecol. Obstet., 122: 3--14, 1966). A dramatic increase in the survival rate is documented for those patients with recurrent melanoma confined to the extremities.</description><subject>Chemotherapy, Cancer, Regional Perfusion</subject><subject>Extremities</subject><subject>Hot Temperature - adverse effects</subject><subject>Hot Temperature - therapeutic use</subject><subject>Humans</subject><subject>Immunity</subject><subject>Melanoma - immunology</subject><subject>Melanoma - therapy</subject><subject>Melphalan - administration & dosage</subject><subject>Neoplasm Metastasis</subject><subject>Recurrence</subject><subject>Skin Neoplasms - immunology</subject><subject>Skin Neoplasms - therapy</subject><issn>0008-5472</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotUM1KxDAYzMG_dfUNPOSkp0KSJk17lEVdYUEQPXgqafKFRpqmJqm6b29l9zTMMDMMc4JWhJC6EFyyC3SZ0udCBSXiHJ1xLjgTK_TxCmkecsLBYhjgG0a8BxXTHYbfCaKDUQP-cbnHPagMBi-inZMLI7YhYg-DGoNX__HcwxLKEbzLDtIVOrVqSHB9xDV6f3x422yL3cvT8-Z-V_S0IrkA0jFKdW1Yw-rGaik6wqGshZVG10IRpgwlWgKjpWCgdKO0rkijNV80I8s1uj30TjF8zZBy613SMCzDIMyplbwilazoYrw5GufOg2mn6LyK-_ZwRfkHlABajw</recordid><startdate>197906</startdate><enddate>197906</enddate><creator>Stehlin, Jr, J S</creator><creator>Giovanella, B C</creator><creator>de Ipolyi, P D</creator><creator>Anderson, R F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197906</creationdate><title>Results of eleven years' experience with heated perfusion for melanoma of the extremities</title><author>Stehlin, Jr, J S ; Giovanella, B C ; de Ipolyi, P D ; Anderson, R F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h160t-e0b211c8d29289fc75b04e385f7dc85a02ad10c7e21352eac9acc609cc47e2d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Chemotherapy, Cancer, Regional Perfusion</topic><topic>Extremities</topic><topic>Hot Temperature - adverse effects</topic><topic>Hot Temperature - therapeutic use</topic><topic>Humans</topic><topic>Immunity</topic><topic>Melanoma - immunology</topic><topic>Melanoma - therapy</topic><topic>Melphalan - administration & dosage</topic><topic>Neoplasm Metastasis</topic><topic>Recurrence</topic><topic>Skin Neoplasms - immunology</topic><topic>Skin Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stehlin, Jr, J S</creatorcontrib><creatorcontrib>Giovanella, B C</creatorcontrib><creatorcontrib>de Ipolyi, P D</creatorcontrib><creatorcontrib>Anderson, R F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer research (Chicago, Ill.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stehlin, Jr, J S</au><au>Giovanella, B C</au><au>de Ipolyi, P D</au><au>Anderson, R F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Results of eleven years' experience with heated perfusion for melanoma of the extremities</atitle><jtitle>Cancer research (Chicago, Ill.)</jtitle><addtitle>Cancer Res</addtitle><date>1979-06</date><risdate>1979</risdate><volume>39</volume><issue>6 Pt 2</issue><spage>2255</spage><epage>2257</epage><pages>2255-2257</pages><issn>0008-5472</issn><abstract>Eleven years have elapsed since we first added heat to regional perfusion for treatment of melanoma of the extremities. This report describes briefly our laboratory findings and our technique of hyperthermic perfusion and brings up to date the survival figures for the 165 patients (185 perfusions) which were originally reported in 1975 (Stehlin et al., Surg. Gynecol. Obstet., 122: 3--14, 1966). A dramatic increase in the survival rate is documented for those patients with recurrent melanoma confined to the extremities.</abstract><cop>United States</cop><pmid>445425</pmid><tpages>3</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; American Association for Cancer Research |
subjects | Chemotherapy, Cancer, Regional Perfusion Extremities Hot Temperature - adverse effects Hot Temperature - therapeutic use Humans Immunity Melanoma - immunology Melanoma - therapy Melphalan - administration & dosage Neoplasm Metastasis Recurrence Skin Neoplasms - immunology Skin Neoplasms - therapy |
title | Results of eleven years' experience with heated perfusion for melanoma of the extremities |
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