On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands

Millions of T cells are produced in the thymus, each expressing a unique alpha/beta T cell receptor (TCR) capable of binding to a foreign peptide in the binding groove of a host major histocompatibility complex (MHC) molecule. T cell-mediated immunity to infection is due to the proliferation and dif...

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Veröffentlicht in:	Annual review of immunology 2010-01, Vol.28 (1), p.275-294
Hauptverfasser:	Jenkins, Marc K, Chu, H Hamlet, McLachlan, James B, Moon, James J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Humans Ligands Major Histocompatibility Complex - immunology Peptides - immunology Receptors, Antigen, T-Cell - immunology T-Lymphocytes - immunology Thymus Gland - immunology
Online-Zugang:	Volltext
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