Identification of novel microRNA targets based on microRNA signatures in bladder cancer

MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate protein‐coding genes. To identify miRNAs that have a tumor suppressive function in bladder cancer (BC), 156 miRNAs were screened in 14 BCs, 5 normal bladder epithelium (NBE) samples and 3 BC cell lines. We identified a subset of 7...

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Veröffentlicht in:	International journal of cancer 2009-07, Vol.125 (2), p.345-352
Hauptverfasser:	Ichimi, Takahiro, Enokida, Hideki, Okuno, Yasushi, Kunimoto, Ryo, Chiyomaru, Takeshi, Kawamoto, Ken, Kawahara, Kazuya, Toki, Kazuki, Kawakami, Kazumori, Nishiyama, Kenryu, Tsujimoto, Gozoh, Nakagawa, Masayuki, Seki, Naohiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Base Sequence Biological and medical sciences bladder cancer Cell Division Female Humans Keratin7 Male Medical sciences microRNA MicroRNAs - genetics Nephrology. Urinary tract diseases Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Small Interfering Tumors Tumors of the urinary system Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology Urinary tract. Prostate gland
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