Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants
Objective To evaluate growth and neurodevelopmental outcomes in preterm very low birth weight (PVLBW) infants treated with oral probiotics for the prevention of necrotizing enterocolitis (NEC). Study design A prospective follow-up study was performed in a cohort of PVLBW infants enrolled in a single...
Gespeichert in:
| Veröffentlicht in: | The Journal of pediatrics 2010-03, Vol.156 (3), p.393-396 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 396 |
|---|---|
| container_issue | 3 |
| container_start_page | 393 |
| container_title | The Journal of pediatrics |
| container_volume | 156 |
| creator | Chou, I-Ching, MD Kuo, Haung-Tsung, MD, PhD Chang, Jeng-Sheng, MD Wu, Shu-Fen, MD Chiu, Hsiao-Yu, MD Su, Bai-Horng, MD, PhD Lin, Hung-Chih, MD |
| description | Objective To evaluate growth and neurodevelopmental outcomes in preterm very low birth weight (PVLBW) infants treated with oral probiotics for the prevention of necrotizing enterocolitis (NEC). Study design A prospective follow-up study was performed in a cohort of PVLBW infants enrolled in a single center with a masked randomized control trial to evaluate the efficacy of oral probiotics in preventing NEC. Growth measures included weight, length, and head circumference. Neurologic and sensory performance was evaluated with standard techniques. Psychometric parameters were measured used the Bayley Scales of Infant Development II (BSID-II). The studies were performed at 3 years corrected age. The primary outcome was death or neurodevelopmental impairment. Results Of the 367 subjects enrolled in trial, 301 (89.9%) were evaluated (153 in the probiotics group and 148 in the control group). There were no significant differences in growth or in any of the neurodevelopmental and sensory outcomes between the 2 groups. Conclusions Oral probiotics given to PVLBW infants at 1 week after birth to reduce the incidence of NEC did not affect growth and neurodevelopmental and sensory outcomes at 3 years corrected age. |
| doi_str_mv | 10.1016/j.jpeds.2009.09.051 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_746008078</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0022347609009664</els_id><sourcerecordid>733671006</sourcerecordid><originalsourceid>FETCH-LOGICAL-c475t-bfc8c367c054f57aa7004c997116f8ac9c63f63e1365b1a2ad6ddd1f1541520a3</originalsourceid><addsrcrecordid>eNqFkl9rFDEUxYModq1-AkHyIj7NejOZycw8KGiptbC4gv8eQza5sdnOJGsy07LfvpnuouBL4UJC-J2Tm5xLyEsGSwZMvN0utzs0aVkCdMu5avaILBh0TSFazh-TBUBZFrxqxAl5ltIWMlgBPCUnrOtYJXi9INNK6WsaLD23FvWY5u06qp5-jWHjwuh0PvL0Iobb8Yoqb-gXnGIweIN92A3ox8yup1GHARN1PutwxDjQnxj3dBVu6UcXs_IXut9XI730VvkxPSdPrOoTvjiup-THp_PvZ5-L1fri8uzDqtBVU4_FxupWc9FoqCtbN0o1AJXuuoYxYVulOy24FRwZF_WGqVIZYYxhltUVq0tQ_JS8OfjuYvgzYRrl4JLGvlcew5RkUwmAFpr2YZLnPhiAyCQ_kDqGlCJauYtuUHEvGcg5GLmV98HIORg5V82y6tXRf9oMaP5pjklk4PURUEmr3kbltUt_ubKs2vx6yNy7A4f5324cRpm0Q6_RuJgDlCa4Bxp5_59e9867fOU17jFtwxR9jkQymUoJ8ts8Q_MIQZdNhKj4HVm6wZg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733671006</pqid></control><display><type>article</type><title>Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Chou, I-Ching, MD ; Kuo, Haung-Tsung, MD, PhD ; Chang, Jeng-Sheng, MD ; Wu, Shu-Fen, MD ; Chiu, Hsiao-Yu, MD ; Su, Bai-Horng, MD, PhD ; Lin, Hung-Chih, MD</creator><creatorcontrib>Chou, I-Ching, MD ; Kuo, Haung-Tsung, MD, PhD ; Chang, Jeng-Sheng, MD ; Wu, Shu-Fen, MD ; Chiu, Hsiao-Yu, MD ; Su, Bai-Horng, MD, PhD ; Lin, Hung-Chih, MD</creatorcontrib><description>Objective To evaluate growth and neurodevelopmental outcomes in preterm very low birth weight (PVLBW) infants treated with oral probiotics for the prevention of necrotizing enterocolitis (NEC). Study design A prospective follow-up study was performed in a cohort of PVLBW infants enrolled in a single center with a masked randomized control trial to evaluate the efficacy of oral probiotics in preventing NEC. Growth measures included weight, length, and head circumference. Neurologic and sensory performance was evaluated with standard techniques. Psychometric parameters were measured used the Bayley Scales of Infant Development II (BSID-II). The studies were performed at 3 years corrected age. The primary outcome was death or neurodevelopmental impairment. Results Of the 367 subjects enrolled in trial, 301 (89.9%) were evaluated (153 in the probiotics group and 148 in the control group). There were no significant differences in growth or in any of the neurodevelopmental and sensory outcomes between the 2 groups. Conclusions Oral probiotics given to PVLBW infants at 1 week after birth to reduce the incidence of NEC did not affect growth and neurodevelopmental and sensory outcomes at 3 years corrected age.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/j.jpeds.2009.09.051</identifier><identifier>PMID: 19914635</identifier><identifier>CODEN: JOPDAB</identifier><language>eng</language><publisher>Maryland Heights, MO: Mosby, Inc</publisher><subject>Administration, Oral ; Age ; Biological and medical sciences ; Child Development ; Child, Preschool ; Developmental Disabilities - etiology ; Developmental Disabilities - prevention & control ; Diseases of mother, fetus and pregnancy ; Enterocolitis, Necrotizing - prevention & control ; Female ; General aspects ; Gynecology. Andrology. Obstetrics ; Humans ; Infant, Newborn ; Infant, Premature - growth & development ; Infant, Very Low Birth Weight - growth & development ; Male ; Medical sciences ; Pediatrics ; Pregnancy. Fetus. Placenta ; Probiotics - administration & dosage ; Randomized Controlled Trials as Topic</subject><ispartof>The Journal of pediatrics, 2010-03, Vol.156 (3), p.393-396</ispartof><rights>Mosby, Inc.</rights><rights>2010 Mosby, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-bfc8c367c054f57aa7004c997116f8ac9c63f63e1365b1a2ad6ddd1f1541520a3</citedby><cites>FETCH-LOGICAL-c475t-bfc8c367c054f57aa7004c997116f8ac9c63f63e1365b1a2ad6ddd1f1541520a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpeds.2009.09.051$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22487000$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19914635$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chou, I-Ching, MD</creatorcontrib><creatorcontrib>Kuo, Haung-Tsung, MD, PhD</creatorcontrib><creatorcontrib>Chang, Jeng-Sheng, MD</creatorcontrib><creatorcontrib>Wu, Shu-Fen, MD</creatorcontrib><creatorcontrib>Chiu, Hsiao-Yu, MD</creatorcontrib><creatorcontrib>Su, Bai-Horng, MD, PhD</creatorcontrib><creatorcontrib>Lin, Hung-Chih, MD</creatorcontrib><title>Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Objective To evaluate growth and neurodevelopmental outcomes in preterm very low birth weight (PVLBW) infants treated with oral probiotics for the prevention of necrotizing enterocolitis (NEC). Study design A prospective follow-up study was performed in a cohort of PVLBW infants enrolled in a single center with a masked randomized control trial to evaluate the efficacy of oral probiotics in preventing NEC. Growth measures included weight, length, and head circumference. Neurologic and sensory performance was evaluated with standard techniques. Psychometric parameters were measured used the Bayley Scales of Infant Development II (BSID-II). The studies were performed at 3 years corrected age. The primary outcome was death or neurodevelopmental impairment. Results Of the 367 subjects enrolled in trial, 301 (89.9%) were evaluated (153 in the probiotics group and 148 in the control group). There were no significant differences in growth or in any of the neurodevelopmental and sensory outcomes between the 2 groups. Conclusions Oral probiotics given to PVLBW infants at 1 week after birth to reduce the incidence of NEC did not affect growth and neurodevelopmental and sensory outcomes at 3 years corrected age.</description><subject>Administration, Oral</subject><subject>Age</subject><subject>Biological and medical sciences</subject><subject>Child Development</subject><subject>Child, Preschool</subject><subject>Developmental Disabilities - etiology</subject><subject>Developmental Disabilities - prevention & control</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Enterocolitis, Necrotizing - prevention & control</subject><subject>Female</subject><subject>General aspects</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature - growth & development</subject><subject>Infant, Very Low Birth Weight - growth & development</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pediatrics</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Probiotics - administration & dosage</subject><subject>Randomized Controlled Trials as Topic</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkl9rFDEUxYModq1-AkHyIj7NejOZycw8KGiptbC4gv8eQza5sdnOJGsy07LfvpnuouBL4UJC-J2Tm5xLyEsGSwZMvN0utzs0aVkCdMu5avaILBh0TSFazh-TBUBZFrxqxAl5ltIWMlgBPCUnrOtYJXi9INNK6WsaLD23FvWY5u06qp5-jWHjwuh0PvL0Iobb8Yoqb-gXnGIweIN92A3ox8yup1GHARN1PutwxDjQnxj3dBVu6UcXs_IXut9XI730VvkxPSdPrOoTvjiup-THp_PvZ5-L1fri8uzDqtBVU4_FxupWc9FoqCtbN0o1AJXuuoYxYVulOy24FRwZF_WGqVIZYYxhltUVq0tQ_JS8OfjuYvgzYRrl4JLGvlcew5RkUwmAFpr2YZLnPhiAyCQ_kDqGlCJauYtuUHEvGcg5GLmV98HIORg5V82y6tXRf9oMaP5pjklk4PURUEmr3kbltUt_ubKs2vx6yNy7A4f5324cRpm0Q6_RuJgDlCa4Bxp5_59e9867fOU17jFtwxR9jkQymUoJ8ts8Q_MIQZdNhKj4HVm6wZg</recordid><startdate>20100301</startdate><enddate>20100301</enddate><creator>Chou, I-Ching, MD</creator><creator>Kuo, Haung-Tsung, MD, PhD</creator><creator>Chang, Jeng-Sheng, MD</creator><creator>Wu, Shu-Fen, MD</creator><creator>Chiu, Hsiao-Yu, MD</creator><creator>Su, Bai-Horng, MD, PhD</creator><creator>Lin, Hung-Chih, MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20100301</creationdate><title>Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants</title><author>Chou, I-Ching, MD ; Kuo, Haung-Tsung, MD, PhD ; Chang, Jeng-Sheng, MD ; Wu, Shu-Fen, MD ; Chiu, Hsiao-Yu, MD ; Su, Bai-Horng, MD, PhD ; Lin, Hung-Chih, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-bfc8c367c054f57aa7004c997116f8ac9c63f63e1365b1a2ad6ddd1f1541520a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Administration, Oral</topic><topic>Age</topic><topic>Biological and medical sciences</topic><topic>Child Development</topic><topic>Child, Preschool</topic><topic>Developmental Disabilities - etiology</topic><topic>Developmental Disabilities - prevention & control</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Enterocolitis, Necrotizing - prevention & control</topic><topic>Female</topic><topic>General aspects</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature - growth & development</topic><topic>Infant, Very Low Birth Weight - growth & development</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pediatrics</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Probiotics - administration & dosage</topic><topic>Randomized Controlled Trials as Topic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chou, I-Ching, MD</creatorcontrib><creatorcontrib>Kuo, Haung-Tsung, MD, PhD</creatorcontrib><creatorcontrib>Chang, Jeng-Sheng, MD</creatorcontrib><creatorcontrib>Wu, Shu-Fen, MD</creatorcontrib><creatorcontrib>Chiu, Hsiao-Yu, MD</creatorcontrib><creatorcontrib>Su, Bai-Horng, MD, PhD</creatorcontrib><creatorcontrib>Lin, Hung-Chih, MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chou, I-Ching, MD</au><au>Kuo, Haung-Tsung, MD, PhD</au><au>Chang, Jeng-Sheng, MD</au><au>Wu, Shu-Fen, MD</au><au>Chiu, Hsiao-Yu, MD</au><au>Su, Bai-Horng, MD, PhD</au><au>Lin, Hung-Chih, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2010-03-01</date><risdate>2010</risdate><volume>156</volume><issue>3</issue><spage>393</spage><epage>396</epage><pages>393-396</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><coden>JOPDAB</coden><abstract>Objective To evaluate growth and neurodevelopmental outcomes in preterm very low birth weight (PVLBW) infants treated with oral probiotics for the prevention of necrotizing enterocolitis (NEC). Study design A prospective follow-up study was performed in a cohort of PVLBW infants enrolled in a single center with a masked randomized control trial to evaluate the efficacy of oral probiotics in preventing NEC. Growth measures included weight, length, and head circumference. Neurologic and sensory performance was evaluated with standard techniques. Psychometric parameters were measured used the Bayley Scales of Infant Development II (BSID-II). The studies were performed at 3 years corrected age. The primary outcome was death or neurodevelopmental impairment. Results Of the 367 subjects enrolled in trial, 301 (89.9%) were evaluated (153 in the probiotics group and 148 in the control group). There were no significant differences in growth or in any of the neurodevelopmental and sensory outcomes between the 2 groups. Conclusions Oral probiotics given to PVLBW infants at 1 week after birth to reduce the incidence of NEC did not affect growth and neurodevelopmental and sensory outcomes at 3 years corrected age.</abstract><cop>Maryland Heights, MO</cop><pub>Mosby, Inc</pub><pmid>19914635</pmid><doi>10.1016/j.jpeds.2009.09.051</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3476 |
| ispartof | The Journal of pediatrics, 2010-03, Vol.156 (3), p.393-396 |
| issn | 0022-3476 1097-6833 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_746008078 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Administration, Oral Age Biological and medical sciences Child Development Child, Preschool Developmental Disabilities - etiology Developmental Disabilities - prevention & control Diseases of mother, fetus and pregnancy Enterocolitis, Necrotizing - prevention & control Female General aspects Gynecology. Andrology. Obstetrics Humans Infant, Newborn Infant, Premature - growth & development Infant, Very Low Birth Weight - growth & development Male Medical sciences Pediatrics Pregnancy. Fetus. Placenta Probiotics - administration & dosage Randomized Controlled Trials as Topic |
| title | Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T00%3A24%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lack%20of%20Effects%20of%20Oral%20Probiotics%20on%20Growth%20and%20Neurodevelopmental%20Outcomes%20in%20Preterm%20Very%20Low%20Birth%20Weight%20Infants&rft.jtitle=The%20Journal%20of%20pediatrics&rft.au=Chou,%20I-Ching,%20MD&rft.date=2010-03-01&rft.volume=156&rft.issue=3&rft.spage=393&rft.epage=396&rft.pages=393-396&rft.issn=0022-3476&rft.eissn=1097-6833&rft.coden=JOPDAB&rft_id=info:doi/10.1016/j.jpeds.2009.09.051&rft_dat=%3Cproquest_cross%3E733671006%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=733671006&rft_id=info:pmid/19914635&rft_els_id=1_s2_0_S0022347609009664&rfr_iscdi=true |