Stabilization of bacteriophage during freeze drying

With preliminary clinical trials completed for the treatment of antibiotic resistant infections using bacteriophages, there is a need to develop pharmaceutically acceptable formulations. Lyophilization is an established technique for the storage of bacteriophage, but there is little consensus regard...

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Veröffentlicht in:	International journal of pharmaceutics 2010-04, Vol.389 (1), p.168-175
Hauptverfasser:	Puapermpoonsiri, U., Ford, S.J., van der Walle, C.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Bacteria Bacteriophage Bacteriophages - chemistry Biological and medical sciences Chemistry, Pharmaceutical - methods Freeze Drying Gelatin - chemistry General pharmacology Lyophilization Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polyethylene Glycols - chemistry Pseudomonas Stabilizers Staphylococcus Sucrose - chemistry Time Factors Transition Temperature
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