Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)-Atom in the Key Hydration Step of Adenosine Deaminase

Conformationally restricted carbocyclic nucleosides with either a northern(N)‐type conformation, i.e., N‐type 2′‐deoxy‐methanocarba‐adenosine 8 ((N)MCdAdo), or a southern(S)‐type conformation, i.e. S‐type 2′‐deoxy‐methanocarba‐adenosine 9, ((S)MCdAdo), were used as substrates for adenosine deaminase...

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Veröffentlicht in:	Helvetica chimica acta 1999-12, Vol.82 (12), p.2119-2129
Hauptverfasser:	Marquez, Victor E., Russ, Pamela, Alonso, Randolph, Siddiqui, Maqbool A., Hernandez, Susana, George, Clifford, Nicklaus, Marc C., Dai, Fang, Ford, Jr, Harry
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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