Infectious prion protein in the filtrate even after 15nm filtration

The evaluation of the removal efficacy during manufacturing is important for the risk assessment of plasma products with respect to possible contamination by infectious prions, as recently reported in several papers on the potential for prion transmission through plasma products. Here, we evaluated...

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Veröffentlicht in:Biologicals 2010-03, Vol.38 (2), p.311-313
Hauptverfasser: Yunoki, Mikihiro, Tanaka, Hiroyuki, Urayama, Takeru, Kanai, Yuta, Nishida, Aya, Yoshikawa, Maki, Ohkubo, Yuji, Kawabata, Yoshiyasu, Hagiwara, Katsuro, Ikuta, Kazuyoshi
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Sprache:eng
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