Resistance of MBL gene-knockout mice to experimental systemic aspergillosis

Abstract Mannose binding lectin (MBL) is a protein of the collectin family that appears important in resistance to invasive pulmonary aspergillosis. We assessed the role of MBL in experimental systemic aspergillosis. MBL-sufficient C57BL/6 (WT) mice and B6.129S4 – Mb11tm1Kata Mb12tm1Kata /J MBL A an...

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Veröffentlicht in:	Immunology letters 2010-02, Vol.128 (2), p.105-107
Hauptverfasser:	Clemons, Karl V, Martinez, Marife, Tong, Ann-Jay, Stevens, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animal model Animals Aspergillosis Aspergillosis - genetics Aspergillosis - immunology Aspergillosis - microbiology Aspergillosis - mortality Aspergillus fumigatus Aspergillus fumigatus - pathogenicity Disease Models, Animal Female Humans Mannose binding lectin Mannose-Binding Lectin - genetics Mannose-Binding Lectin - metabolism MBL Mice Mice, Congenic Mice, Inbred C57BL Mice, Knockout Survival Analysis
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