Dietary selenium plus folic acid as an antioxidant therapy for ethanol-exposed pups

BACKGROUND: Nutrients such as folic acid and selenium are decreased in dams exposed to ethanol during gestation and lactation, affecting their metabolism, antioxidant balance, and the future health of their progeny. We will study whether the supplementation of the maternal diet with folate and selen...

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Veröffentlicht in:	Birth defects research. Part B. Developmental and reproductive toxicology 2009-12, Vol.86 (6), p.490-495
Hauptverfasser:	Ojeda, M. L., Nogales, F., Jotty, K., Barrero, M. J., Murillo, M. L., Carreras, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - adverse effects Alcohol Drinking - metabolism Animals Animals, Newborn - growth & development Animals, Newborn - metabolism antioxidant enzymes Antioxidants - administration & dosage Diet Dietary Supplements Drug Combinations Ethanol - adverse effects ethanol toxicity Female Fetal Alcohol Spectrum Disorders - etiology Fetal Alcohol Spectrum Disorders - prevention & control folic acid Folic Acid - administration & dosage Glutathione Peroxidase - metabolism Lactation - drug effects Lipid Peroxidation - drug effects Liver - drug effects Liver - metabolism Male offspring rats Oxidative Stress - drug effects Pregnancy Prenatal Exposure Delayed Effects - metabolism Prenatal Exposure Delayed Effects - prevention & control Protein Carbonylation - drug effects Rats Rats, Wistar selenium Selenium - administration & dosage
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