Comet Assay in Evaluating DNA Damage Associated With Ischaemia-Reperfusion Injury in Patients Undergoing Coronary Surgery

Ischaemia-reperfusion (I/R) injury is responsible for a number of conditions such as coronary bypass and myocardial infarction, and deaths. Oxygen-free radicals formed during I/R have been proposed as the leading causes of tissue injury, and they play an important role in I/R injury. I/R induces oxi...

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Veröffentlicht in:	Arhiv za higijenu rada i toksikologiju 2009-09, Vol.60 (3), p.307-315
Hauptverfasser:	Karahalil, Bensu (Faculty of Pharmacy, Toxicology Department, Gazi University, Ankara, Turkey), Gumus, Tulin (Ministry of Health, Ataturk Training and Research Hospital, Ankara, Turkey), Emerce, Esra (Faculty of Pharmacy, Toxicology Department, Gazi University, Ankara, Turkey), Izdes, Seval (Ministry of Health, Ataturk Training and Research Hospital, Ankara, Turkey), Kanbak, Orhan (Ministry of Health, Ataturk Training and Research Hospital, Ankara, Turkey), Kesimci, Elvin (Ministry of Health, Ataturk Training and Research Hospital, Ankara, Turkey)
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anesthesia, General Comet Assay Coronary Artery Bypass - adverse effects coronary artery bypass graft surgery DNA Damage DNA lesions Female Humans I/R koronarne arterije lactate Lactic Acid - blood Male Middle Aged Myocardial Reperfusion Injury - diagnosis Myocardial Reperfusion Injury - genetics razine laktata u serumu reactive oxygen species reaktivni kisikovi radikali Smoking ugradnja premosnice
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