The Hepatitis C Virus 5'UTR Genomic Region Remains Highly Conserved Under HAART: A 4- to 8-Year Longitudinal Study from HCV/HIV Co-Infected Patients
IT HAS BEEN REPORTED that hepatitis C virus (HCV) may be lymphotropic in the setting of human immunodeficiency virus type 1 (HIV-1) coinfection. In HTV-infected subjects, HCV may replicate in the same cells as HIV-1, which increases the opportunity for direct interactions between these pathogens. Wi...
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Veröffentlicht in: | AIDS research and human retroviruses 2010-05, Vol.26 (5), p.527-532 |
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container_title | AIDS research and human retroviruses |
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creator | MORETTI, Franco BOLCIC, Federico MAMMANA, Lilia BELEN BOUZAS, Maria LAUFER, Natalia QUARLERI, Jorge |
description | IT HAS BEEN REPORTED that hepatitis C virus (HCV) may be lymphotropic in the setting of human immunodeficiency virus type 1 (HIV-1) coinfection. In HTV-infected subjects, HCV may replicate in the same cells as HIV-1, which increases the opportunity for direct interactions between these pathogens. Without any antiviral-therapy pressure, both viruses could establish a competitive relation for this particular cellular scenario super(1). |
doi_str_mv | 10.1089/aid.2009.0237 |
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In HTV-infected subjects, HCV may replicate in the same cells as HIV-1, which increases the opportunity for direct interactions between these pathogens. Without any antiviral-therapy pressure, both viruses could establish a competitive relation for this particular cellular scenario super(1).</description><identifier>ISSN: 0889-2229</identifier><identifier>EISSN: 1931-8405</identifier><identifier>DOI: 10.1089/aid.2009.0237</identifier><identifier>PMID: 20455757</identifier><identifier>CODEN: ARHRE7</identifier><language>eng</language><publisher>New Rochelle, NY: Liebert</publisher><subject>5' Untranslated Regions - genetics ; Adult ; Antiretroviral Therapy, Highly Active - utilization ; Base Sequence ; Biological and medical sciences ; Conserved Sequence ; Drug therapy ; Female ; Fundamental and applied biological sciences. Psychology ; Genetic Variation ; Genome, Viral - drug effects ; Genome, Viral - genetics ; Health aspects ; Hepacivirus - classification ; Hepacivirus - drug effects ; Hepacivirus - genetics ; Hepacivirus - isolation & purification ; Hepatitis C ; Hepatitis C virus ; Hepatitis C, Chronic - complications ; Hepatitis C, Chronic - virology ; Highly active antiretroviral therapy ; HIV infection ; HIV Infections - complications ; HIV Infections - drug therapy ; Human immunodeficiency virus 1 ; Human viral diseases ; Humans ; Infectious diseases ; Longitudinal Studies ; Male ; Medical sciences ; Microbiology ; Middle Aged ; Miscellaneous ; Molecular Sequence Data ; Retrovirus ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. 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In HTV-infected subjects, HCV may replicate in the same cells as HIV-1, which increases the opportunity for direct interactions between these pathogens. Without any antiviral-therapy pressure, both viruses could establish a competitive relation for this particular cellular scenario super(1).</description><subject>5' Untranslated Regions - genetics</subject><subject>Adult</subject><subject>Antiretroviral Therapy, Highly Active - utilization</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>Conserved Sequence</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetic Variation</subject><subject>Genome, Viral - drug effects</subject><subject>Genome, Viral - genetics</subject><subject>Health aspects</subject><subject>Hepacivirus - classification</subject><subject>Hepacivirus - drug effects</subject><subject>Hepacivirus - genetics</subject><subject>Hepacivirus - isolation & purification</subject><subject>Hepatitis C</subject><subject>Hepatitis C virus</subject><subject>Hepatitis C, Chronic - complications</subject><subject>Hepatitis C, Chronic - virology</subject><subject>Highly active antiretroviral therapy</subject><subject>HIV infection</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - drug therapy</subject><subject>Human immunodeficiency virus 1</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Molecular Sequence Data</subject><subject>Retrovirus</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. 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Psychology</topic><topic>Genetic Variation</topic><topic>Genome, Viral - drug effects</topic><topic>Genome, Viral - genetics</topic><topic>Health aspects</topic><topic>Hepacivirus - classification</topic><topic>Hepacivirus - drug effects</topic><topic>Hepacivirus - genetics</topic><topic>Hepacivirus - isolation & purification</topic><topic>Hepatitis C</topic><topic>Hepatitis C virus</topic><topic>Hepatitis C, Chronic - complications</topic><topic>Hepatitis C, Chronic - virology</topic><topic>Highly active antiretroviral therapy</topic><topic>HIV infection</topic><topic>HIV Infections - complications</topic><topic>HIV Infections - drug therapy</topic><topic>Human immunodeficiency virus 1</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Microbiology</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Molecular Sequence Data</topic><topic>Retrovirus</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. 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subjects | 5' Untranslated Regions - genetics Adult Antiretroviral Therapy, Highly Active - utilization Base Sequence Biological and medical sciences Conserved Sequence Drug therapy Female Fundamental and applied biological sciences. Psychology Genetic Variation Genome, Viral - drug effects Genome, Viral - genetics Health aspects Hepacivirus - classification Hepacivirus - drug effects Hepacivirus - genetics Hepacivirus - isolation & purification Hepatitis C Hepatitis C virus Hepatitis C, Chronic - complications Hepatitis C, Chronic - virology Highly active antiretroviral therapy HIV infection HIV Infections - complications HIV Infections - drug therapy Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Longitudinal Studies Male Medical sciences Microbiology Middle Aged Miscellaneous Molecular Sequence Data Retrovirus Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology |
title | The Hepatitis C Virus 5'UTR Genomic Region Remains Highly Conserved Under HAART: A 4- to 8-Year Longitudinal Study from HCV/HIV Co-Infected Patients |
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