Interleukin-1b-induced apoptosis through adenylyl cyclase and ERK1/2 inhibition in primary cultured thyroid cells

The programmed cell death plays a crucial role in the regulation of numerous physiological and pathological phenomena. In this study, we show that interleukin-1 b (IL-1b) induces an early production of endogenous ceramides via N-sphingomyelinase (N-Smase) as well as an inhibition of adenylyl cyclase...

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Veröffentlicht in:	Biochemical and biophysical research communications 2006-01, Vol.339 (2), p.469-476
Hauptverfasser:	El Btaouri, H, Rath, G, Morjani, H, Schneider, C, Petitfrere, E, Antonicelli, F, Martiny, L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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