Rituximab treatment of stiff-person syndrome in a patient with thymoma, diabetes mellitus and autoimmune thyroiditis

Abstract Stiff-person syndrome (SPS) is an autoimmune neurological disorder characterized by stiffness of the skeletal muscle with superimposed spasms and production of autoantibodies to glutamic acid decarboxylase (GAD) and amphiphysin. The disorder results from B cell-mediated clonal production of...

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Veröffentlicht in:	Journal of clinical neuroscience 2010-03, Vol.17 (3), p.389-391
Hauptverfasser:	Dupond, J.L, Essalmi, L, Gil, H, Meaux-Ruault, N, Hafsaoui, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-amphiphysin antibodies Anti-glutamic acid decarboxylase antibodies Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Murine-Derived Diabetes Mellitus - physiopathology Humans Immunologic Factors - therapeutic use Male Middle Aged Neurology Rituximab Stiff-person syndrome Stiff-Person Syndrome - drug therapy Stiff-Person Syndrome - etiology Thymoma Thymoma - complications Thyroiditis, Autoimmune - complications
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