A Critical Role for Peroxisomal Proliferator-Activated Receptor-{alpha} Nuclear Receptors in the Development of Cardiomyocyte Degeneration and Necrosis
Peroxisomal proliferator-activated receptor (PPAR)-g is a ligand-activated transcriptional factor that regulates genes involved in lipid metabolism and energy homeostasis. PPAR-g activators, including fibrates, have been used to treat dyslipidemia for several decades. In contrast to their known effe...
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Veröffentlicht in: | The American journal of pathology 2006-09, Vol.169 (3), p.750-760 |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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