A Critical Role for Peroxisomal Proliferator-Activated Receptor-{alpha} Nuclear Receptors in the Development of Cardiomyocyte Degeneration and Necrosis

Peroxisomal proliferator-activated receptor (PPAR)-g is a ligand-activated transcriptional factor that regulates genes involved in lipid metabolism and energy homeostasis. PPAR-g activators, including fibrates, have been used to treat dyslipidemia for several decades. In contrast to their known effe...

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Veröffentlicht in:The American journal of pathology 2006-09, Vol.169 (3), p.750-760
Hauptverfasser: Pruimboom-Brees, Ingrid, Haghpassand, Mehrdad, Royer, Lori, Brees, Dominique, Aldinger, Charles, Reagan, William, Singh, Jatinder, Kerlin, Roy, Kane, Christopher, Bagley, Scott, Hayward, Cheryl, Loy, James, O'Brien, Peter, Francone, Omar L
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Sprache:eng
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