Residues of persistent organic pollutants (POPs) in human milk in Hong Kong

Data on pesticide body load in the south China region are scarce. Here, we report the concentrations of 24 persistent organic pollutants (POPs), in 10 pools of human milk samples, collected at 2–6 weeks postpartum from 238 primiparous women living in Hong Kong and south China, who participated in th...

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Veröffentlicht in:Chemosphere (Oxford) 2010-04, Vol.79 (3), p.259-265
Hauptverfasser: Hedley, A.J., Hui, L.L., Kypke, K., Malisch, R., van Leeuwen, F.X.R., Moy, G., Wong, T.W., Nelson, E.A.S.
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container_end_page 265
container_issue 3
container_start_page 259
container_title Chemosphere (Oxford)
container_volume 79
creator Hedley, A.J.
Hui, L.L.
Kypke, K.
Malisch, R.
van Leeuwen, F.X.R.
Moy, G.
Wong, T.W.
Nelson, E.A.S.
description Data on pesticide body load in the south China region are scarce. Here, we report the concentrations of 24 persistent organic pollutants (POPs), in 10 pools of human milk samples, collected at 2–6 weeks postpartum from 238 primiparous women living in Hong Kong and south China, who participated in the 2002–2003 WHO exposure study. Residues were determined by gas chromatography with electron capture detector and confirmed by gas chromatography with mass spectrometry. The mean levels of alpha-HCH (mean 0.6 ng g −1 fat), beta-HCH (940 ng g −1 fat), gamma-HCH (1.8 ng g −1 fat), dieldrin (1.0 ng g −1 fat) and HCB (21.8 ng g −1 fat) were much lower than the 1985 estimates. Mean levels of alpha-HCH, gamma-HCH, dieldrin, cis-heptachlor-epoxide (0.7 ng g −1 fat), sum-chlordane (6.1 ng g −1 fat), trans-nonachlor (12.0 ng g −1 fat), BDE 47 (1.9 ng g −1 fat) and sum PBDE (3.4 ng g −1 fat) were comparable to the international median levels of the 15 other countries participating in the 2002–03 WHO exposure study. Hong Kong had the highest level of beta-HCH, possibly a residual effect of previous high exposures in the 1970s. Body loads of beta-HCH and chlordane were lower among mothers with younger age while mothers born in mainland China had lower levels of beta-HCH, cis-heptachlor-epoxide, oxy-chlordane and trans-nonachlor. Levels of toxaphene, endrin, endosulfan, bromcyclene and nitrofen were not detected in all or almost all of the milk pools. Continuous monitoring of POPs in human milk, especially beta-HCH, is needed for surveillance and interpretation of time trends, and for linkage to strict enforcement of agricultural regulations.
doi_str_mv 10.1016/j.chemosphere.2010.01.047
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Here, we report the concentrations of 24 persistent organic pollutants (POPs), in 10 pools of human milk samples, collected at 2–6 weeks postpartum from 238 primiparous women living in Hong Kong and south China, who participated in the 2002–2003 WHO exposure study. Residues were determined by gas chromatography with electron capture detector and confirmed by gas chromatography with mass spectrometry. The mean levels of alpha-HCH (mean 0.6 ng g −1 fat), beta-HCH (940 ng g −1 fat), gamma-HCH (1.8 ng g −1 fat), dieldrin (1.0 ng g −1 fat) and HCB (21.8 ng g −1 fat) were much lower than the 1985 estimates. Mean levels of alpha-HCH, gamma-HCH, dieldrin, cis-heptachlor-epoxide (0.7 ng g −1 fat), sum-chlordane (6.1 ng g −1 fat), trans-nonachlor (12.0 ng g −1 fat), BDE 47 (1.9 ng g −1 fat) and sum PBDE (3.4 ng g −1 fat) were comparable to the international median levels of the 15 other countries participating in the 2002–03 WHO exposure study. 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Here, we report the concentrations of 24 persistent organic pollutants (POPs), in 10 pools of human milk samples, collected at 2–6 weeks postpartum from 238 primiparous women living in Hong Kong and south China, who participated in the 2002–2003 WHO exposure study. Residues were determined by gas chromatography with electron capture detector and confirmed by gas chromatography with mass spectrometry. The mean levels of alpha-HCH (mean 0.6 ng g −1 fat), beta-HCH (940 ng g −1 fat), gamma-HCH (1.8 ng g −1 fat), dieldrin (1.0 ng g −1 fat) and HCB (21.8 ng g −1 fat) were much lower than the 1985 estimates. Mean levels of alpha-HCH, gamma-HCH, dieldrin, cis-heptachlor-epoxide (0.7 ng g −1 fat), sum-chlordane (6.1 ng g −1 fat), trans-nonachlor (12.0 ng g −1 fat), BDE 47 (1.9 ng g −1 fat) and sum PBDE (3.4 ng g −1 fat) were comparable to the international median levels of the 15 other countries participating in the 2002–03 WHO exposure study. Hong Kong had the highest level of beta-HCH, possibly a residual effect of previous high exposures in the 1970s. Body loads of beta-HCH and chlordane were lower among mothers with younger age while mothers born in mainland China had lower levels of beta-HCH, cis-heptachlor-epoxide, oxy-chlordane and trans-nonachlor. Levels of toxaphene, endrin, endosulfan, bromcyclene and nitrofen were not detected in all or almost all of the milk pools. Continuous monitoring of POPs in human milk, especially beta-HCH, is needed for surveillance and interpretation of time trends, and for linkage to strict enforcement of agricultural regulations.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>20199797</pmid><doi>10.1016/j.chemosphere.2010.01.047</doi><tpages>7</tpages></addata></record>
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subjects Adolescent
Adult
Applied sciences
Biological and medical sciences
breast milk
chemical residues
Chlordan - analysis
Chromatography, Gas
Demography
Dieldrin
Endrin
environmental exposure
Environmental Exposure - analysis
Exact sciences and technology
Female
Gas chromatography
Halogenated Diphenyl Ethers - analysis
HCH (pesticide)
Hong Kong
Human
Human milk
Humans
Isomerism
Lindane - analysis
Mass Spectrometry
Medical sciences
Milk
Milk, Human - chemistry
organochlorine insecticides
organochlorine pesticides
Pearl River Delta
Persistent organic pollutants
Pesticide
pesticide residues
Pesticide Residues - analysis
Pesticide Residues - classification
Pesticides, fertilizers and other agrochemicals toxicology
Pollutants
Pollution
Pools
Postpartum Period
Pregnancy
Residues
Risk Factors
Socioeconomic Factors
Toxicology
Young Adult
title Residues of persistent organic pollutants (POPs) in human milk in Hong Kong
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