Melatonin reduces locomotor activity and circulating cortisol in goldfish
The present study focused on the effects of a subchronic melatonin treatment on locomotor activity and cortisol plasma levels in goldfish. We compared two different administration routes: peripheral (10 μg/g body weight) versus central (1 μg/μl) injections of melatonin for 7 or 4 days, respectively....
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| Veröffentlicht in: | Hormones and behavior 2010-03, Vol.57 (3), p.323-329 |
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| creator | Azpeleta, Clara Martínez-Álvarez, Rosa María Delgado, María Jesús Isorna, Esther De Pedro, Nuria |
| description | The present study focused on the effects of a subchronic melatonin treatment on locomotor activity and cortisol plasma levels in goldfish. We compared two different administration routes: peripheral (10 μg/g body weight)
versus central (1 μg/μl) injections of melatonin for 7 or 4 days, respectively. Daily locomotor activity, including both diurnal and nocturnal activities, food anticipatory activity and circulating cortisol at 11:00 (under 24 h of food deprivation and 17 h postinjection) were significantly reduced after repeated intraperitoneal injections with melatonin for 7 days, but not after intracerebroventricular treatment. Taking in mind the anoretic effect of melatonin in this species, we investigated if such feeding reduction is directly responsible for the reduction in motor activity induced by melatonin treatment. Food restriction (50%) for 10 days did not significantly modify either daily locomotor activity or plasma cortisol levels in goldfish, indicating that the peripheral action of melatonin diminishing locomotor activity in goldfish is not a direct consequence of its anoretic action. In summary, our results indicate that, as previously described in other vertebrate species, melatonin can regulate locomotor activity and cortisol levels in goldfish, suggesting a sedative effect of this hormone in this teleost. |
| doi_str_mv | 10.1016/j.yhbeh.2010.01.001 |
| format | Article |
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In summary, our results indicate that, as previously described in other vertebrate species, melatonin can regulate locomotor activity and cortisol levels in goldfish, suggesting a sedative effect of this hormone in this teleost.</description><subject>Animal behavior</subject><subject>Animals</subject><subject>Behavioral psychophysiology</subject><subject>Biological and medical sciences</subject><subject>Carassius auratus</subject><subject>Cortisol</subject><subject>Diet</subject><subject>Feeding</subject><subject>Feeding Behavior - physiology</subject><subject>Fish</subject><subject>Food Deprivation - physiology</subject><subject>Freshwater</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Goldfish</subject><subject>Goldfish - physiology</subject><subject>Hormones and behavior</subject><subject>Hydrocortisone - blood</subject><subject>Hydrocortisone - metabolism</subject><subject>Locomotor activity</subject><subject>Melatonin</subject><subject>Melatonin - metabolism</subject><subject>Motor Activity - physiology</subject><subject>Movement</subject><subject>Photoperiod</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. Psychophysiology</subject><subject>Radioimmunoassay</subject><subject>Stress</subject><subject>Teleostei</subject><subject>Time Factors</subject><issn>0018-506X</issn><issn>1095-6867</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9v1DAQxS0EokvhEyChCAlxyuKJYzs5cKgq_lQq6gUkbpY9nnS9ysbFTirtt8ftLiBxaE-jGf_eaPweY6-Br4GD-rBd7zeONuuGlwmHNefwhK2A97JWndJP2apMulpy9fOEvch5W1qQbfucnTSc6163sGIX32i0c5zCVCXyC1KuxohxF-eYKotzuA3zvrKTrzAkXAobpusKY5pDjmNVZNdx9EPIm5fs2WDHTK-O9ZT9-Pzp-_nX-vLqy8X52WWNbavnmhwKLZz3zmGnhcaBO-eEa7jTEiyUdxIcrZVSqcF5aNwgAXrSAAOSF6fs_WHvTYq_Fsqz2YWMNI52orhko1vZNx0o_TgpBHRtJ7tCvv2P3MYlTeUbBvq261Xf8AKJA4Qp5pxoMDcp7GzaG-DmLhGzNfeJmLtEDAdTDC-qN8fVi9uR_6v5E0EB3h0Bm9GOQ7IThvyPa6RWsheF-3jgqJh7GyiZjIGmYklIhLPxMTx4yG-SHqtv</recordid><startdate>20100301</startdate><enddate>20100301</enddate><creator>Azpeleta, Clara</creator><creator>Martínez-Álvarez, Rosa María</creator><creator>Delgado, María Jesús</creator><creator>Isorna, Esther</creator><creator>De Pedro, Nuria</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier BV</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope></search><sort><creationdate>20100301</creationdate><title>Melatonin reduces locomotor activity and circulating cortisol in goldfish</title><author>Azpeleta, Clara ; Martínez-Álvarez, Rosa María ; Delgado, María Jesús ; Isorna, Esther ; De Pedro, Nuria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-ebc373bddbbc8737cf0bbb3b20b751a1ebce30caa5566fbd12bf5119e711fced3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Animal behavior</topic><topic>Animals</topic><topic>Behavioral psychophysiology</topic><topic>Biological and medical sciences</topic><topic>Carassius auratus</topic><topic>Cortisol</topic><topic>Diet</topic><topic>Feeding</topic><topic>Feeding Behavior - physiology</topic><topic>Fish</topic><topic>Food Deprivation - physiology</topic><topic>Freshwater</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Goldfish</topic><topic>Goldfish - physiology</topic><topic>Hormones and behavior</topic><topic>Hydrocortisone - blood</topic><topic>Hydrocortisone - metabolism</topic><topic>Locomotor activity</topic><topic>Melatonin</topic><topic>Melatonin - metabolism</topic><topic>Motor Activity - physiology</topic><topic>Movement</topic><topic>Photoperiod</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Radioimmunoassay</topic><topic>Stress</topic><topic>Teleostei</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Azpeleta, Clara</creatorcontrib><creatorcontrib>Martínez-Álvarez, Rosa María</creatorcontrib><creatorcontrib>Delgado, María Jesús</creatorcontrib><creatorcontrib>Isorna, Esther</creatorcontrib><creatorcontrib>De Pedro, Nuria</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Hormones and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Azpeleta, Clara</au><au>Martínez-Álvarez, Rosa María</au><au>Delgado, María Jesús</au><au>Isorna, Esther</au><au>De Pedro, Nuria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Melatonin reduces locomotor activity and circulating cortisol in goldfish</atitle><jtitle>Hormones and behavior</jtitle><addtitle>Horm Behav</addtitle><date>2010-03-01</date><risdate>2010</risdate><volume>57</volume><issue>3</issue><spage>323</spage><epage>329</epage><pages>323-329</pages><issn>0018-506X</issn><eissn>1095-6867</eissn><coden>HOBEAO</coden><abstract>The present study focused on the effects of a subchronic melatonin treatment on locomotor activity and cortisol plasma levels in goldfish. We compared two different administration routes: peripheral (10 μg/g body weight)
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| subjects | Animal behavior Animals Behavioral psychophysiology Biological and medical sciences Carassius auratus Cortisol Diet Feeding Feeding Behavior - physiology Fish Food Deprivation - physiology Freshwater Fundamental and applied biological sciences. Psychology Goldfish Goldfish - physiology Hormones and behavior Hydrocortisone - blood Hydrocortisone - metabolism Locomotor activity Melatonin Melatonin - metabolism Motor Activity - physiology Movement Photoperiod Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Radioimmunoassay Stress Teleostei Time Factors |
| title | Melatonin reduces locomotor activity and circulating cortisol in goldfish |
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