MRP1 Polymorphisms Associated With Citalopram Response in Patients With Major Depression

Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic variatio...

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Veröffentlicht in:	Journal of clinical psychopharmacology 2010-04, Vol.30 (2), p.116-125
Hauptverfasser:	SUNG HEE LEE, LEE, Min-Soo, MIN GOO LEE, JI HYUN LEE, SO WON KIM, KANG, Rhee-Hun, CHOI, Myoung-Jin, SANG JIN PARK, SE JOO KIM, JAE MYUN LEE, COLE, Susan P. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Aged Biological and medical sciences Citalopram - therapeutic use Depression Depressive Disorder, Major - drug therapy Depressive Disorder, Major - genetics Depressive Disorder, Major - psychology Female Follow-Up Studies Gene Frequency - genetics Genetic Variation - genetics Humans Male Medical sciences Middle Aged Mood disorders Multidrug Resistance-Associated Proteins - genetics Neuropharmacology Pharmacology. Drug treatments Polymorphism, Single Nucleotide - genetics Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Treatment Outcome Young Adult
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