In situ identification of mononuclear cells infiltrating cutaneous carcinoma: an immuno-histochemical study
The present study was undertaken in order to investigate the exact nature of the cells surrounding cutaneous tumours. Formalin-fixed, paraffin-embedded sections were tested with a horse antihuman T lymphocyte serum and with IgG, IgA and IgM rabbit antihuman serum. All the sections were respectively...
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| Veröffentlicht in: | Acta dermato-venereologica 1979, Vol.59 (3), p.219-222 |
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| container_title | Acta dermato-venereologica |
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| creator | De Panfilis, G Colli, V Manfredi, G Misk, I Rima, S Zampetti, M Allegra, F |
| description | The present study was undertaken in order to investigate the exact nature of the cells surrounding cutaneous tumours. Formalin-fixed, paraffin-embedded sections were tested with a horse antihuman T lymphocyte serum and with IgG, IgA and IgM rabbit antihuman serum. All the sections were respectively treated with rabbit anti-horse or swine antirabbit peroxidase-labelled serum. The advantages offered by the immunoperoxidase technique are briefly discussed. T cells are in overwhelming proportion in comparison with IgG, IgA and IgM bearing cells. This seems a further demonstration that mononuclear infiltrate surrounding cutaneous carcinoma mainly represents a cell-mediated immune response. |
| doi_str_mv | 10.2340/0001555559219222 |
| format | Article |
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Formalin-fixed, paraffin-embedded sections were tested with a horse antihuman T lymphocyte serum and with IgG, IgA and IgM rabbit antihuman serum. All the sections were respectively treated with rabbit anti-horse or swine antirabbit peroxidase-labelled serum. The advantages offered by the immunoperoxidase technique are briefly discussed. T cells are in overwhelming proportion in comparison with IgG, IgA and IgM bearing cells. 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Formalin-fixed, paraffin-embedded sections were tested with a horse antihuman T lymphocyte serum and with IgG, IgA and IgM rabbit antihuman serum. All the sections were respectively treated with rabbit anti-horse or swine antirabbit peroxidase-labelled serum. The advantages offered by the immunoperoxidase technique are briefly discussed. T cells are in overwhelming proportion in comparison with IgG, IgA and IgM bearing cells. 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Formalin-fixed, paraffin-embedded sections were tested with a horse antihuman T lymphocyte serum and with IgG, IgA and IgM rabbit antihuman serum. All the sections were respectively treated with rabbit anti-horse or swine antirabbit peroxidase-labelled serum. The advantages offered by the immunoperoxidase technique are briefly discussed. T cells are in overwhelming proportion in comparison with IgG, IgA and IgM bearing cells. This seems a further demonstration that mononuclear infiltrate surrounding cutaneous carcinoma mainly represents a cell-mediated immune response.</abstract><cop>Sweden</cop><pmid>87078</pmid><doi>10.2340/0001555559219222</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-5555 |
| ispartof | Acta dermato-venereologica, 1979, Vol.59 (3), p.219-222 |
| issn | 0001-5555 1651-2057 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Carcinoma, Basal Cell - immunology Carcinoma, Basal Cell - pathology Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - pathology Humans Immunoenzyme Techniques Immunoglobulin A - analysis Immunoglobulin G - analysis Immunoglobulin M - analysis Immunoglobulins - analysis Lymphocytes - immunology Neoplasm Metastasis Skin Neoplasms - immunology Skin Neoplasms - pathology T-Lymphocytes - immunology |
| title | In situ identification of mononuclear cells infiltrating cutaneous carcinoma: an immuno-histochemical study |
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