Marek's Disease Virus–Induced Immunosuppression: Array Analysis of Chicken Immune Response Gene Expression Profiling

Marek's disease (MD) is a lymphoproliferative disease of chickens induced by a highly cell-associated oncogenic α-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latency infection within CD4 + T cells. Host-virus interaction, immune respons...

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Veröffentlicht in:	Viral immunology 2010-06, Vol.23 (3), p.39-319
Hauptverfasser:	Heidari, Mohammad, Sarson, Aimie J., Huebner, Marianne, Sharif, Shayan, Kireev, Dmitry, Zhou, Huaijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Animals Chickens Gene expression Gene Expression Profiling Genes, MHC Class II Genetic aspects Health aspects Immune response Immune Tolerance Leukocytes, Mononuclear - immunology Mardivirus - immunology Mardivirus - pathogenicity Marek Disease - immunology Marek's disease Marek's disease herpesvirus Oligonucleotide Array Sequence Analysis Prevention Risk factors Spleen - immunology
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