Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons

Transcriptional regulation of gene expression is thought to play a pivotal role in activity‐dependent neuronal differentiation and circuit formation. Here, we investigated the role of histone deacetylase 9 (HDAC9), which regulates transcription by histone modification, in the development of neocorti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The European journal of neuroscience 2010-05, Vol.31 (9), p.1521-1532
Hauptverfasser:	Sugo, Noriyuki, Oshiro, Hiroaki, Takemura, Mitsuhiro, Kobayashi, Toshiaki, Kohno, Yusuke, Uesaka, Naofumi, Song, Wen-Jie, Yamamoto, Nobuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Active Transport, Cell Nucleus Animals Cell Enlargement Cell Line, Tumor Cell Nucleus - metabolism Cells, Cultured cerebral cortex Chromatin - metabolism Cytoplasm - metabolism dendrite Dendrites - physiology differentiation Gene Expression Regulation, Developmental Histone Deacetylases - genetics Histone Deacetylases - metabolism histone modification Mice Mice, Inbred C57BL Neocortex - cytology Neocortex - physiology Neurons - cytology Neurons - physiology Proto-Oncogene Proteins c-fos - metabolism Rats Rats, Sprague-Dawley Repressor Proteins - genetics Repressor Proteins - metabolism rodent
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!