Distinct Roles of Myosin Va in Membrane Remodeling and Exocytosis of Secretory Granules

Hormone- and neuropeptide-containing secretory granules (SGs) of neuroendocrine PC12 cells are formed at the trans- Golgi network as immature SGs. These intermediates are converted to mature SGs in a complex maturation process, including matrix condensation, processing of cargo proteins and removal...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2010-05, Vol.11 (5), p.637-650
Hauptverfasser:	Kögel, Tanja, Rudolf, Rüdiger, Hodneland, Erlend, Hellwig, Andrea, Kuznetsov, Sergei A, Seiler, Florian, Söllner, Thomas H, Barroso, João, Gerdes, Hans-Hermann
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Actins - metabolism Animals Calcium - metabolism Cellular Structures - metabolism Clathrin-Coated Vesicles exocytosis Exocytosis - physiology furin Furin - metabolism hormone maturation Membrane Proteins - metabolism Membranes - metabolism myosin Va myosin Vb PC12 Cells processing Rats secretory granules Secretory Vesicles - metabolism Secretory Vesicles - physiology
Online-Zugang:	Volltext
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