A new multiparameter assay to assess HPV 16/18, viral load and physical status together with gain of telomerase genes in HPV‐related cancers

Oncogenic human papillomavirus (HPV) is the most important risk factor for cancer of the uterine cervix and a subgroup of head and neck cancers. Viral load has been associated with persistence of infection, whereas integration of HPV into the host cell genome is associated with transition to invasiv...

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Veröffentlicht in:	International journal of cancer 2010-02, Vol.126 (4), p.959-975
Hauptverfasser:	Theelen, Wendy, Reijans, Martin, Simons, Guus, Ramaekers, Frans C.S., Speel, Ernst‐Jan M., Hopman, Anton H.N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alphapapillomavirus - genetics Biological and medical sciences DNA Primers Female Female genital diseases Gene Amplification Genome, Viral Gynecology. Andrology. Obstetrics head and neck cancer Head and Neck Neoplasms - virology HeLa Cells - virology Human papillomavirus 16 Human papillomavirus 16 - isolation & purification Human papillomavirus 18 - isolation & purification Humans Medical sciences Middle Aged Papillomavirus Infections - complications Plasmids - genetics Telomerase - genetics TERC TERT Tumors uterine cervical cancer Uterine Cervical Neoplasms - virology viral integration Viral Load - methods
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