Serum-derived MHC class II molecules: Potent regulators of the cellular and humoral immune response

Abstract Soluble MHC antigens are detected in body fluids but their role and origin are still unclear. This study examined whether serum IA antigens, isolated from BALB/c mice (sIAd ), could modulate the immune response. Specific purification procedures isolated intact IA molecules, which were there...

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Veröffentlicht in:	Immunobiology (1979) 2010-03, Vol.215 (3), p.194-205
Hauptverfasser:	Marios-Frankiskos, Sardis, Panagiota, Miltiadou, Katerina, Bakela, Athanassakis, Irene
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Allergy and Immunology Animals B-Lymphocytes - immunology Blotting, Western Body fluids CD4-Positive T-Lymphocytes - immunology Cellular immune response Cytokines Electrophoresis, Polyacrylamide Gel Enzyme-Linked Immunosorbent Assay HLA-D Antigens - blood HLA-D Antigens - immunology Humoral immune response Immunity, Cellular Immunity, Humoral Legionella pneumophila Lymphocyte Activation - immunology Lymphocyte Culture Test, Mixed Mice Mice, Inbred BALB C Mice, Inbred C3H Microscopy, Confocal Mitogenic response Soluble MHC class II
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