$Antidiabetic and antihyperlipidemic activity of ethyl acetate:Isopropanol (1:1) fraction of Vernonia anthelmintica seeds in Streptozotocin induced diabetic rats$

Antidiabetic and antihyperlipidemic activity of ethyl acetate:Isopropanol (1:1) fraction of Vernonia anthelmintica seeds in Streptozotocin induced diabetic rats

Ethanolic extract prepared from the seeds of Vernonia anthelmintica was evaluated for its antihyperglycemic activity in STZ (Streptozotocin) induced diabetic rats. Administration of ethanolic extract at a dosage of 0.50 g/kg bw produced the maximum fall (82%) in the blood glucose levels in diabetic...

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Veröffentlicht in:	Food and chemical toxicology 2010-02, Vol.48 (2), p.495-501
Hauptverfasser:	Fatima, Shaik Sameena, Rajasekhar, Maddirala Dilip, Kumar, Kondeti Vinay, Kumar, Mekala Thur Sampath, Babu, Kasetti Ramesh, Rao, Chippada Appa
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Propanol - chemistry Acetates - chemistry Active fraction animal disease models Animals Antihyperglycemic antihyperlipidemic Biological and medical sciences blood glucose Blood Glucose - analysis Blood Glucose - drug effects blood lipids Chemical and industrial products toxicology. Toxic occupational diseases Chemical Fractionation cholesteremic effect Chromatography, Gel diabetes mellitus Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - drug therapy Diabetes. Impaired glucose tolerance dosage Endocrine pancreas. Apud cells (diseases) Endocrinopathies Ethanol - chemistry Ethanolic extract ethnobotany Etiopathogenesis. Screening. Investigations. Target tissue resistance free fatty acids Glyburide - pharmacology glycemic effect Hydroxymethylglutaryl CoA Reductases - metabolism Hypoglycemic Agents - pharmacology Hypolipidemic Agents - pharmacology Insulin - blood Lipid Metabolism - drug effects Lipids - blood Medical sciences oxidative stress Phytotherapy - methods Plant Extracts - pharmacology Plant poisons toxicology Rats seed extracts Seeds - chemistry Solvents Streptozocin Streptozotocin Toxicology Vernonia Vernonia - chemistry Vernonia anthelmintica seeds
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