Overexpression of cytochrome P450 genes in pyrethroid-resistant Culex quinquefasciatus

JPal-per strain of Culex quinquefasciatus exhibits extremely high resistance against pyrethroids in larvae, though the resistance is greatly lower in adults. Increased microsome monooxygenase metabolism is one of the major factors of the larval resistance in this strain. We cloned 46 novel cytochrom...

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Veröffentlicht in:	Insect biochemistry and molecular biology 2010-02, Vol.40 (2), p.146-152
Hauptverfasser:	Komagata, Osamu, Kasai, Shinji, Tomita, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	adult insects Animals Base Sequence complementary DNA Culex - genetics Culex quinquefasciatus cytochrome P-450 Cytochrome P-450 Enzyme System - genetics Cytochrome P450 monooxygenase, Insecticide resistance gene expression regulation hematophagous insects insect pests insect vectors Insecticide Resistance larvae metabolic detoxification Microarray microarray technology microsomes molecular sequence data nucleotide sequences oxygenases Pyrethrins Pyrethroid pyrethroid insecticides strain differences transcription (genetics)
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