Recurrent pulmonary disease in children: a complication of gastroesophageal reflux

To evaluate the role of gastroesophageal reflux (GER) as a possible cause of recurrent pulmonary disease, 30 children, aged 1 to 18 years, were studied prospectively with esophageal function tests. These included esophagram (30 patients), esophageal manometry (29 patients), pH probe (Tuttle) test (2...

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Veröffentlicht in:Pediatrics (Evanston) 1979-01, Vol.63 (1), p.47-51
Hauptverfasser: Euler, A R, Byrne, W J, Ament, M E, Fonkalsrud, E W, Strobel, C T, Siegel, S C, Katz, R M, Rachelefsky, G S
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container_end_page 51
container_issue 1
container_start_page 47
container_title Pediatrics (Evanston)
container_volume 63
creator Euler, A R
Byrne, W J
Ament, M E
Fonkalsrud, E W
Strobel, C T
Siegel, S C
Katz, R M
Rachelefsky, G S
description To evaluate the role of gastroesophageal reflux (GER) as a possible cause of recurrent pulmonary disease, 30 children, aged 1 to 18 years, were studied prospectively with esophageal function tests. These included esophagram (30 patients), esophageal manometry (29 patients), pH probe (Tuttle) test (29 patients), and esophagoscopy with esophageal biopsy (23 patients). The patients studied had either chronic asthma or two or more documented pneumonias within a one-year period. Nineteen (63%) had GER based on two or more positive tests. Eighteen had positive Tuttle tests; 13 had abnormal manometry studies; nine had esophagitis on biopsy; six had esophagitis on esophagoscopy; and five had reflux on esophagram. Of those with GER, 17 had a history of nocturnal cough and eight vomited during infancy. Children with recurrent pulmonary disease should have esophageal function testing to exclude GER as the cause.
doi_str_mv 10.1542/peds.63.1.47
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subjects Adolescent
Asthma - etiology
Child
Child, Preschool
Chronic Disease
Female
Gastroesophageal Reflux - complications
Humans
Infant
Lung Diseases - etiology
Male
Pneumonia - etiology
Recurrence
title Recurrent pulmonary disease in children: a complication of gastroesophageal reflux
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