Behavioral side effects in rats treated with acetylcholinesterase inhibitors suggested used as prophylactics against nerve agents

Acetylcholinesterase inhibitors in combination with an anticholinergic, particularly anticholinergics with antiglutamatergic properties, can effectively protect against nerve agent-induced seizures and lethality. The objective of the present study was to examine potential behavioral side effects of...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2010-05, Vol.95 (3), p.338-343
Hauptverfasser:	Myhrer, Trond, Enger, Siri, Aas, Pål
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase inhibitors Animals Biological and medical sciences Chemical Warfare Agents - toxicity Cholinesterase Inhibitors - toxicity Cognition Disorders - chemically induced Cognition Disorders - enzymology Male Medical sciences Motor Activity - drug effects Motor Activity - physiology Nerve agents Procyclidine Procyclidine - toxicity Prophylactics Rats Rats, Wistar Reduced activity
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