Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation
Purpose To assess the diagnostic performance of a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors for nuclear myocardial perfusion imaging (MPI). Methods The study group comprised 75 consecutive patients (55 men, BMI range 19–45 kg/m 2 ) who...
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| Veröffentlicht in: | European journal of nuclear medicine and molecular imaging 2010-04, Vol.37 (4), p.773-778 |
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| container_title | European journal of nuclear medicine and molecular imaging |
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| creator | Buechel, Ronny R. Herzog, Bernhard A. Husmann, Lars Burger, Irene A. Pazhenkottil, Aju P. Treyer, Valerie Valenta, Ines von Schulthess, Patrick Nkoulou, René Wyss, Christophe A. Kaufmann, Philipp A. |
| description | Purpose
To assess the diagnostic performance of a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors for nuclear myocardial perfusion imaging (MPI).
Methods
The study group comprised 75 consecutive patients (55 men, BMI range 19–45 kg/m
2
) who underwent a 1-day
99m
Tc-tetrofosmin adenosine-stress/rest imaging protocol. Scanning was performed first on a conventional dual-detector SPECT gamma camera (Ventri, GE Healthcare) with a 15-min acquisition time each for stress and rest. All scans were immediately repeated on an ultrafast CZT camera (Discovery 530 NMc, GE Healthcare) with a 3-min scan time for stress and a 2-min scan time for rest. Clinical agreement (normal, ischaemia, scar) between CZT and SPECT was assessed for each patient and for each coronary territory using SPECT MPI as the reference standard. Segmental myocardial tracer uptake values (percent of maximum) using a 20-segment model and left ventricular ejection fraction (EF) values obtained using CZT were compared with those obtained using conventional SPECT by intraclass correlation and by calculating Bland-Altman limits of agreement.
Results
There was excellent clinical agreement between CZT and conventional SPECT on a per-patient basis (96.0%) and on a per-vessel territory basis (96.4%) as shown by a highly significant correlation between segmental tracer uptake values (
r
=0.901,
p |
| doi_str_mv | 10.1007/s00259-009-1375-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_745688976</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733370648</sourcerecordid><originalsourceid>FETCH-LOGICAL-c445t-58403e73af88f010df32320f5c2d77e8403826b1627d1762d000d895e90613083</originalsourceid><addsrcrecordid>eNqFkd9qFTEQxoNYbD36AN5I8MartZNkN3-8k6JWKHhjr0OaTE5TdrPHZNfSB-h7m-OpFQTxagbml--byUfIKwbvGIA6rQB8MB2A6ZhQQ6eekBMmmekUaPP0sVdwTJ7XegPANNfmGTnmwEApLU7I_eW4FBddXWhe_Yiu0Olu9q6E5Ea6wxLXmuZM0-S2KW9pax3NeEu3bpoc9W7C4uhtWq5pxSn5OYfVL3OhARf81bRyndP3Fd_TmErz8WPKyTf1H25MwS1N_gU5im6s-PKhbsjlp4_fzs67i6-fv5x9uOh83w9LN-geBCrhotaxnRCi4IJDHDwPSuF-qrm8YpKrwJTkAQCCNgMakEyAFhvy9qC7K3PbqC52StXjOLqM81qt6geptVHy_6QQQoHs95pv_iJv5rXkdoblrJcDA2EaxA6QL3OtBaPdlfal5c4ysPss7SFL27K0-yybwYa8fhBeryYMjy9-h9cAfgBqG-Utlj_O_1b9CTG8qfE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>214651039</pqid></control><display><type>article</type><title>Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Buechel, Ronny R. ; Herzog, Bernhard A. ; Husmann, Lars ; Burger, Irene A. ; Pazhenkottil, Aju P. ; Treyer, Valerie ; Valenta, Ines ; von Schulthess, Patrick ; Nkoulou, René ; Wyss, Christophe A. ; Kaufmann, Philipp A.</creator><creatorcontrib>Buechel, Ronny R. ; Herzog, Bernhard A. ; Husmann, Lars ; Burger, Irene A. ; Pazhenkottil, Aju P. ; Treyer, Valerie ; Valenta, Ines ; von Schulthess, Patrick ; Nkoulou, René ; Wyss, Christophe A. ; Kaufmann, Philipp A.</creatorcontrib><description>Purpose
To assess the diagnostic performance of a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors for nuclear myocardial perfusion imaging (MPI).
Methods
The study group comprised 75 consecutive patients (55 men, BMI range 19–45 kg/m
2
) who underwent a 1-day
99m
Tc-tetrofosmin adenosine-stress/rest imaging protocol. Scanning was performed first on a conventional dual-detector SPECT gamma camera (Ventri, GE Healthcare) with a 15-min acquisition time each for stress and rest. All scans were immediately repeated on an ultrafast CZT camera (Discovery 530 NMc, GE Healthcare) with a 3-min scan time for stress and a 2-min scan time for rest. Clinical agreement (normal, ischaemia, scar) between CZT and SPECT was assessed for each patient and for each coronary territory using SPECT MPI as the reference standard. Segmental myocardial tracer uptake values (percent of maximum) using a 20-segment model and left ventricular ejection fraction (EF) values obtained using CZT were compared with those obtained using conventional SPECT by intraclass correlation and by calculating Bland-Altman limits of agreement.
Results
There was excellent clinical agreement between CZT and conventional SPECT on a per-patient basis (96.0%) and on a per-vessel territory basis (96.4%) as shown by a highly significant correlation between segmental tracer uptake values (
r
=0.901,
p
<0.001). Similarly, EF values for both scanners were highly correlated (
r
=0.976,
p
<0.001) with narrow Bland-Altman limits of agreement (−5.5–10.6%).
Conclusion
The novel CZT camera allows a more than fivefold reduction in scan time and provides clinical information equivalent to conventional standard SPECT MPI.</description><identifier>ISSN: 1619-7070</identifier><identifier>EISSN: 1619-7089</identifier><identifier>DOI: 10.1007/s00259-009-1375-7</identifier><identifier>PMID: 20107783</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adenosine ; Adult ; Aged ; Aged, 80 and over ; Cadmium ; Cardiology ; Clinical trials ; Equipment Design ; Exercise Test ; Female ; Gamma Cameras ; Heart - diagnostic imaging ; Humans ; Imaging ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Myocardial Perfusion Imaging - instrumentation ; Myocardial Perfusion Imaging - methods ; NMR ; Nuclear magnetic resonance ; Nuclear Medicine ; Observer Variation ; Oncology ; Organophosphorus Compounds ; Organotechnetium Compounds ; Original Article ; Orthopedics ; Radiology ; Radiopharmaceuticals ; Semiconductors ; Single-Blind Method ; Tellurium ; Time Factors ; Tomography, Emission-Computed, Single-Photon - instrumentation ; Zinc</subject><ispartof>European journal of nuclear medicine and molecular imaging, 2010-04, Vol.37 (4), p.773-778</ispartof><rights>Springer-Verlag 2009</rights><rights>Springer-Verlag 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c445t-58403e73af88f010df32320f5c2d77e8403826b1627d1762d000d895e90613083</citedby><cites>FETCH-LOGICAL-c445t-58403e73af88f010df32320f5c2d77e8403826b1627d1762d000d895e90613083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00259-009-1375-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00259-009-1375-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20107783$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Buechel, Ronny R.</creatorcontrib><creatorcontrib>Herzog, Bernhard A.</creatorcontrib><creatorcontrib>Husmann, Lars</creatorcontrib><creatorcontrib>Burger, Irene A.</creatorcontrib><creatorcontrib>Pazhenkottil, Aju P.</creatorcontrib><creatorcontrib>Treyer, Valerie</creatorcontrib><creatorcontrib>Valenta, Ines</creatorcontrib><creatorcontrib>von Schulthess, Patrick</creatorcontrib><creatorcontrib>Nkoulou, René</creatorcontrib><creatorcontrib>Wyss, Christophe A.</creatorcontrib><creatorcontrib>Kaufmann, Philipp A.</creatorcontrib><title>Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation</title><title>European journal of nuclear medicine and molecular imaging</title><addtitle>Eur J Nucl Med Mol Imaging</addtitle><addtitle>Eur J Nucl Med Mol Imaging</addtitle><description>Purpose
To assess the diagnostic performance of a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors for nuclear myocardial perfusion imaging (MPI).
Methods
The study group comprised 75 consecutive patients (55 men, BMI range 19–45 kg/m
2
) who underwent a 1-day
99m
Tc-tetrofosmin adenosine-stress/rest imaging protocol. Scanning was performed first on a conventional dual-detector SPECT gamma camera (Ventri, GE Healthcare) with a 15-min acquisition time each for stress and rest. All scans were immediately repeated on an ultrafast CZT camera (Discovery 530 NMc, GE Healthcare) with a 3-min scan time for stress and a 2-min scan time for rest. Clinical agreement (normal, ischaemia, scar) between CZT and SPECT was assessed for each patient and for each coronary territory using SPECT MPI as the reference standard. Segmental myocardial tracer uptake values (percent of maximum) using a 20-segment model and left ventricular ejection fraction (EF) values obtained using CZT were compared with those obtained using conventional SPECT by intraclass correlation and by calculating Bland-Altman limits of agreement.
Results
There was excellent clinical agreement between CZT and conventional SPECT on a per-patient basis (96.0%) and on a per-vessel territory basis (96.4%) as shown by a highly significant correlation between segmental tracer uptake values (
r
=0.901,
p
<0.001). Similarly, EF values for both scanners were highly correlated (
r
=0.976,
p
<0.001) with narrow Bland-Altman limits of agreement (−5.5–10.6%).
Conclusion
The novel CZT camera allows a more than fivefold reduction in scan time and provides clinical information equivalent to conventional standard SPECT MPI.</description><subject>Adenosine</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cadmium</subject><subject>Cardiology</subject><subject>Clinical trials</subject><subject>Equipment Design</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Gamma Cameras</subject><subject>Heart - diagnostic imaging</subject><subject>Humans</subject><subject>Imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Myocardial Perfusion Imaging - instrumentation</subject><subject>Myocardial Perfusion Imaging - methods</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Nuclear Medicine</subject><subject>Observer Variation</subject><subject>Oncology</subject><subject>Organophosphorus Compounds</subject><subject>Organotechnetium Compounds</subject><subject>Original Article</subject><subject>Orthopedics</subject><subject>Radiology</subject><subject>Radiopharmaceuticals</subject><subject>Semiconductors</subject><subject>Single-Blind Method</subject><subject>Tellurium</subject><subject>Time Factors</subject><subject>Tomography, Emission-Computed, Single-Photon - instrumentation</subject><subject>Zinc</subject><issn>1619-7070</issn><issn>1619-7089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkd9qFTEQxoNYbD36AN5I8MartZNkN3-8k6JWKHhjr0OaTE5TdrPHZNfSB-h7m-OpFQTxagbml--byUfIKwbvGIA6rQB8MB2A6ZhQQ6eekBMmmekUaPP0sVdwTJ7XegPANNfmGTnmwEApLU7I_eW4FBddXWhe_Yiu0Olu9q6E5Ea6wxLXmuZM0-S2KW9pax3NeEu3bpoc9W7C4uhtWq5pxSn5OYfVL3OhARf81bRyndP3Fd_TmErz8WPKyTf1H25MwS1N_gU5im6s-PKhbsjlp4_fzs67i6-fv5x9uOh83w9LN-geBCrhotaxnRCi4IJDHDwPSuF-qrm8YpKrwJTkAQCCNgMakEyAFhvy9qC7K3PbqC52StXjOLqM81qt6geptVHy_6QQQoHs95pv_iJv5rXkdoblrJcDA2EaxA6QL3OtBaPdlfal5c4ysPss7SFL27K0-yybwYa8fhBeryYMjy9-h9cAfgBqG-Utlj_O_1b9CTG8qfE</recordid><startdate>20100401</startdate><enddate>20100401</enddate><creator>Buechel, Ronny R.</creator><creator>Herzog, Bernhard A.</creator><creator>Husmann, Lars</creator><creator>Burger, Irene A.</creator><creator>Pazhenkottil, Aju P.</creator><creator>Treyer, Valerie</creator><creator>Valenta, Ines</creator><creator>von Schulthess, Patrick</creator><creator>Nkoulou, René</creator><creator>Wyss, Christophe A.</creator><creator>Kaufmann, Philipp A.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20100401</creationdate><title>Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation</title><author>Buechel, Ronny R. ; Herzog, Bernhard A. ; Husmann, Lars ; Burger, Irene A. ; Pazhenkottil, Aju P. ; Treyer, Valerie ; Valenta, Ines ; von Schulthess, Patrick ; Nkoulou, René ; Wyss, Christophe A. ; Kaufmann, Philipp A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-58403e73af88f010df32320f5c2d77e8403826b1627d1762d000d895e90613083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adenosine</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cadmium</topic><topic>Cardiology</topic><topic>Clinical trials</topic><topic>Equipment Design</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Gamma Cameras</topic><topic>Heart - diagnostic imaging</topic><topic>Humans</topic><topic>Imaging</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Myocardial Perfusion Imaging - instrumentation</topic><topic>Myocardial Perfusion Imaging - methods</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Nuclear Medicine</topic><topic>Observer Variation</topic><topic>Oncology</topic><topic>Organophosphorus Compounds</topic><topic>Organotechnetium Compounds</topic><topic>Original Article</topic><topic>Orthopedics</topic><topic>Radiology</topic><topic>Radiopharmaceuticals</topic><topic>Semiconductors</topic><topic>Single-Blind Method</topic><topic>Tellurium</topic><topic>Time Factors</topic><topic>Tomography, Emission-Computed, Single-Photon - instrumentation</topic><topic>Zinc</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Buechel, Ronny R.</creatorcontrib><creatorcontrib>Herzog, Bernhard A.</creatorcontrib><creatorcontrib>Husmann, Lars</creatorcontrib><creatorcontrib>Burger, Irene A.</creatorcontrib><creatorcontrib>Pazhenkottil, Aju P.</creatorcontrib><creatorcontrib>Treyer, Valerie</creatorcontrib><creatorcontrib>Valenta, Ines</creatorcontrib><creatorcontrib>von Schulthess, Patrick</creatorcontrib><creatorcontrib>Nkoulou, René</creatorcontrib><creatorcontrib>Wyss, Christophe A.</creatorcontrib><creatorcontrib>Kaufmann, Philipp A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>European journal of nuclear medicine and molecular imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Buechel, Ronny R.</au><au>Herzog, Bernhard A.</au><au>Husmann, Lars</au><au>Burger, Irene A.</au><au>Pazhenkottil, Aju P.</au><au>Treyer, Valerie</au><au>Valenta, Ines</au><au>von Schulthess, Patrick</au><au>Nkoulou, René</au><au>Wyss, Christophe A.</au><au>Kaufmann, Philipp A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation</atitle><jtitle>European journal of nuclear medicine and molecular imaging</jtitle><stitle>Eur J Nucl Med Mol Imaging</stitle><addtitle>Eur J Nucl Med Mol Imaging</addtitle><date>2010-04-01</date><risdate>2010</risdate><volume>37</volume><issue>4</issue><spage>773</spage><epage>778</epage><pages>773-778</pages><issn>1619-7070</issn><eissn>1619-7089</eissn><abstract>Purpose
To assess the diagnostic performance of a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors for nuclear myocardial perfusion imaging (MPI).
Methods
The study group comprised 75 consecutive patients (55 men, BMI range 19–45 kg/m
2
) who underwent a 1-day
99m
Tc-tetrofosmin adenosine-stress/rest imaging protocol. Scanning was performed first on a conventional dual-detector SPECT gamma camera (Ventri, GE Healthcare) with a 15-min acquisition time each for stress and rest. All scans were immediately repeated on an ultrafast CZT camera (Discovery 530 NMc, GE Healthcare) with a 3-min scan time for stress and a 2-min scan time for rest. Clinical agreement (normal, ischaemia, scar) between CZT and SPECT was assessed for each patient and for each coronary territory using SPECT MPI as the reference standard. Segmental myocardial tracer uptake values (percent of maximum) using a 20-segment model and left ventricular ejection fraction (EF) values obtained using CZT were compared with those obtained using conventional SPECT by intraclass correlation and by calculating Bland-Altman limits of agreement.
Results
There was excellent clinical agreement between CZT and conventional SPECT on a per-patient basis (96.0%) and on a per-vessel territory basis (96.4%) as shown by a highly significant correlation between segmental tracer uptake values (
r
=0.901,
p
<0.001). Similarly, EF values for both scanners were highly correlated (
r
=0.976,
p
<0.001) with narrow Bland-Altman limits of agreement (−5.5–10.6%).
Conclusion
The novel CZT camera allows a more than fivefold reduction in scan time and provides clinical information equivalent to conventional standard SPECT MPI.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>20107783</pmid><doi>10.1007/s00259-009-1375-7</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1619-7070 |
| ispartof | European journal of nuclear medicine and molecular imaging, 2010-04, Vol.37 (4), p.773-778 |
| issn | 1619-7070 1619-7089 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adenosine Adult Aged Aged, 80 and over Cadmium Cardiology Clinical trials Equipment Design Exercise Test Female Gamma Cameras Heart - diagnostic imaging Humans Imaging Male Medicine Medicine & Public Health Middle Aged Myocardial Perfusion Imaging - instrumentation Myocardial Perfusion Imaging - methods NMR Nuclear magnetic resonance Nuclear Medicine Observer Variation Oncology Organophosphorus Compounds Organotechnetium Compounds Original Article Orthopedics Radiology Radiopharmaceuticals Semiconductors Single-Blind Method Tellurium Time Factors Tomography, Emission-Computed, Single-Photon - instrumentation Zinc |
| title | Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation |
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