Carbonic anhydrase IX and human papillomavirus as diagnostic biomarkers of cervical dysplasia/neoplasia in women with a cytologic diagnosis of atypical glandular cells: A Gynecologic Oncology Group study in United States

High‐risk human papillomavirus (H‐HPV) infection is strongly linked to cervical neoplasia, but its role in detecting glandular lesions (GLs) is unclear. In the cervix, carbonic anhydrase IX (CA‐IX) is expressed in cervical neoplasia, but rarely in the benign cervix. The diagnostic utility of these b...

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Veröffentlicht in:	International journal of cancer 2009-11, Vol.125 (10), p.2434-2440
Hauptverfasser:	Liao, Shu‐Yuan, Rodgers, William H., Kauderer, James, Bonfiglio, Thomas A., Walker, Joan L., Darcy, Kathleen M., Carter, Randy, Hatae, Masayuji, Levine, Lyuba, Spirtos, Nick M., Stanbridge, Eric J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - diagnosis Adenocarcinoma - enzymology Adenocarcinoma - virology Adult AGC diagnosis Aged Aged, 80 and over Antigens, Neoplasm - metabolism Biological and medical sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carbonic Anhydrase IX Carbonic Anhydrases - metabolism Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - virology CA‐IX Cervical Intraepithelial Neoplasia - diagnosis Cervical Intraepithelial Neoplasia - enzymology Cervical Intraepithelial Neoplasia - virology cervix Cytodiagnosis DNA, Viral - genetics Female Female genital diseases Genotype Gynecology. Andrology. Obstetrics HPV Human papillomavirus Humans Immunoenzyme Techniques Medical sciences Middle Aged Neoplasm Invasiveness Neoplasm Staging Neoplasms, Glandular and Epithelial - diagnosis Neoplasms, Glandular and Epithelial - enzymology Neoplasms, Glandular and Epithelial - virology Papanicolaou Test Papillomaviridae - genetics Papillomaviridae - isolation & purification Papillomavirus Infections - diagnosis Papillomavirus Infections - enzymology Papillomavirus Infections - virology Polymerase Chain Reaction Retrospective Studies Risk Factors Sensitivity and Specificity Tumors Uterine Cervical Neoplasms - diagnosis Uterine Cervical Neoplasms - enzymology Uterine Cervical Neoplasms - virology Vaginal Smears Young Adult
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