Protein biosynthesis in isolated human scalp hair follicles

Protein biosynthesis in isolated human scalp hair follicles

The present study demonstrates that protein biosynthesis can be studied in single isolated human scalp hair follicles. The matrix and the sheath are the main regions where amino acids are built in. Incorporation is linear for at least five hours. The newly synthesized proteins can be separated into...

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Veröffentlicht in:Molecular biology reports 1979-02, Vol.4 (4), p.211-216
Hauptverfasser: Vermorken, A J, Weterings, P J, Bloemendal, H
Format: Artikel
Sprache:eng
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Electrophoresis, Polyacrylamide Gel
Hair - metabolism
Humans
Methionine - metabolism
Protein Biosynthesis
Proteins - analysis
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container_title Molecular biology reports
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creator Vermorken, A J
Weterings, P J
Bloemendal, H
description The present study demonstrates that protein biosynthesis can be studied in single isolated human scalp hair follicles. The matrix and the sheath are the main regions where amino acids are built in. Incorporation is linear for at least five hours. The newly synthesized proteins can be separated into a water-soluble, a urea-soluble and a urea-insoluble fraction. Product analysis has been performed on the first two fractions, revealing different protein patterns.
doi_str_mv 10.1007/BF00777556
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subjects Electrophoresis, Polyacrylamide Gel
Hair - metabolism
Humans
Methionine - metabolism
Protein Biosynthesis
Proteins - analysis
title Protein biosynthesis in isolated human scalp hair follicles
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