Rapid decay of tumoricidal activity and loss of responsiveness to lymphokines in inflammatory macrophages

The ability of inflammatory tissue macrophages harvested on glass coverslips implanted in the s.c. tissue of C57BL/6 mice to kill tumor cells in vitro has been examined. Macrophage present on coverslips implanted for less than 4 days are devoid of spontaneous tumoricidal activity but can be rendered...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1979-07, Vol.39 (7 Pt 1), p.2582-2590
Hauptverfasser:	Poste, G, Kirsh, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cytotoxicity, Immunologic Inflammation - immunology Lymphokines - pharmacology Macrophages - cytology Macrophages - immunology Melanoma - immunology Mice Mice, Inbred C57BL Neoplasms, Experimental - immunology Peroxidases Staining and Labeling Time Factors
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