Localization of low molecular weight 99mTc-labeled dimercaptodicarboxylic acids in kidney tissue

Kidney localization of low molecular weight 99mTc-di-mercaptodicarboxylic acid complexes was examined in mice. The complexes 99mTc-dimercaptosuccinic acid, 99mTc-dimercaptoglutaric acid, and 99mTc-dimercaptoadipic acid were formed by reducing sodium 99mTc-pertechnetate with stannous chloride in the...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1979-05, Vol.68 (5), p.621-623
Hauptverfasser:	Kubiatowicz, David O., Bolles, Theodore F., Nora, James C., Ithakissios, Dionyssis S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carboxylic Acids - metabolism Female Hydrogen-Ion Concentration Kidney - diagnostic imaging Kidney - metabolism Kidney-radionuclide imaging Kidney—radionuclide imaging, technetium mercaptan complexes, structure-activity relationships localization in kidney tissue low molecular weight Mice Molecular Weight Radionuclide Imaging Radionuclide imaging, renal—technetium mercaptan complexes, low molecular weight, localization in kidney tissue, synthesis, structure-activity relationships renal-technetium mercaptan complexes Structure-Activity Relationship structure-activity relationships Structure-activity relationships-technetium mercaptan complexes Structure-activity relationships—technetium mercaptan complexes, localization in kidney tissue Sulfhydryl Compounds - metabolism synthesis Technetium technetium mercaptan complexes Technetium mercaptan complexes-localization in kidney tissue Technetium mercaptan complexes—localization in kidney tissue, synthesis, low molecular weight, structure-activity relationships Tissue Distribution
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