Estrogen Replacement Therapy I: A 10-Year Prospective Study in the Relationship to Osteoporosis
A 10-year, double-blind prospective study was undertaken to evaluate the effects of estrogen replacement therapy. The sample population consisted of 84 pairs of randomly chosen postmenopausal patients who were matched for age and diagnosis. One half of the patients received conjugated estrogens and...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1979-03, Vol.53 (3), p.277-281 |
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container_title | Obstetrics and gynecology (New York. 1953) |
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creator | NACHTIGALL, LILA E NACHTIGALL, RICHARD H NACHTIGALL, ROBERT D BECKMAN, E MARK |
description | A 10-year, double-blind prospective study was undertaken to evaluate the effects of estrogen replacement therapy. The sample population consisted of 84 pairs of randomly chosen postmenopausal patients who were matched for age and diagnosis. One half of the patients received conjugated estrogens and cyclic progesterone, while the other half received placebo. Estrogen-treated patients whose therapy started within 3 years of menopause showed improvement or no increase in osteoporosis. Control patients demonstrate an increase in their osteoporosis. |
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Control patients demonstrate an increase in their osteoporosis.</description><subject>Clinical Trials as Topic</subject><subject>Double-Blind Method</subject><subject>Estrogens, Conjugated (USP) - pharmacology</subject><subject>Estrogens, Conjugated (USP) - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Medroxyprogesterone - pharmacology</subject><subject>Medroxyprogesterone - therapeutic use</subject><subject>Menopause - drug effects</subject><subject>Osteoporosis - prevention & control</subject><subject>Prospective Studies</subject><subject>Time Factors</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotkMtOwzAURCPEqxT-gIVX7CL5GTvsqqpApUpFUCRYRY5zQwJpbGyHqn9PULu6mjtnZjEnyYQoyVLK2PtpMsGY5qlUnF8mVyF8YYxJlrOL5JwSRQSZJMUiRG8_oUcv4DptYAt9RJsGvHZ7tLxHM0Rw-gHao2dvgwMT219Ar3Go9qjtUWxgTHY6trYPTetQtGgdIlhnR7wN18lZrbsAN8c7Td4eFpv5U7paPy7ns1XqSCZIylRZYVGbioGsTEV1nWElOcFcVjirieCCE6hNbbghwnBRllSJjFJVZpAzyqbJ3aHXefszQIjFtg0Guk73YIdQSM5zJXM2grdHcCi3UBXOt1vt98VhkNHmB3tnuwg-fHfDDnzRgO5iU4z74YwKnJJc5piNKv1_EfYHMW1ssw</recordid><startdate>197903</startdate><enddate>197903</enddate><creator>NACHTIGALL, LILA E</creator><creator>NACHTIGALL, RICHARD H</creator><creator>NACHTIGALL, ROBERT D</creator><creator>BECKMAN, E MARK</creator><general>The American College of Obstetricians and Gynecologists</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197903</creationdate><title>Estrogen Replacement Therapy I: A 10-Year Prospective Study in the Relationship to Osteoporosis</title><author>NACHTIGALL, LILA E ; NACHTIGALL, RICHARD H ; NACHTIGALL, ROBERT D ; BECKMAN, E MARK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1651-38bd05fcd3e7dcd2af608741047d06f154541efcfc4c15c45bb2856228b6e9323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Clinical Trials as Topic</topic><topic>Double-Blind Method</topic><topic>Estrogens, Conjugated (USP) - pharmacology</topic><topic>Estrogens, Conjugated (USP) - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Medroxyprogesterone - pharmacology</topic><topic>Medroxyprogesterone - therapeutic use</topic><topic>Menopause - drug effects</topic><topic>Osteoporosis - prevention & control</topic><topic>Prospective Studies</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NACHTIGALL, LILA E</creatorcontrib><creatorcontrib>NACHTIGALL, RICHARD H</creatorcontrib><creatorcontrib>NACHTIGALL, ROBERT D</creatorcontrib><creatorcontrib>BECKMAN, E MARK</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NACHTIGALL, LILA E</au><au>NACHTIGALL, RICHARD H</au><au>NACHTIGALL, ROBERT D</au><au>BECKMAN, E MARK</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Estrogen Replacement Therapy I: A 10-Year Prospective Study in the Relationship to Osteoporosis</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1979-03</date><risdate>1979</risdate><volume>53</volume><issue>3</issue><spage>277</spage><epage>281</epage><pages>277-281</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><abstract>A 10-year, double-blind prospective study was undertaken to evaluate the effects of estrogen replacement therapy. 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ispartof | Obstetrics and gynecology (New York. 1953), 1979-03, Vol.53 (3), p.277-281 |
issn | 0029-7844 1873-233X |
language | eng |
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source | MEDLINE; Journals@Ovid Complete |
subjects | Clinical Trials as Topic Double-Blind Method Estrogens, Conjugated (USP) - pharmacology Estrogens, Conjugated (USP) - therapeutic use Female Humans Medroxyprogesterone - pharmacology Medroxyprogesterone - therapeutic use Menopause - drug effects Osteoporosis - prevention & control Prospective Studies Time Factors |
title | Estrogen Replacement Therapy I: A 10-Year Prospective Study in the Relationship to Osteoporosis |
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