The arginine-rich peptide from cytosol of Guerin epithelioma

The arginine-rich peptide from cytosol of Guerin epithelioma

Arginine-rich peptide from cytosol of Guerin epitheliomas has been isolated and characterized. It contains 212.0 arginine residues, 77.1 lysine and 36.9 histidine residues per 1000 residues of amino acids. The ratio of basic to the acidic amino acids amounted to 1.23. The peptide has a cationic char...

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Veröffentlicht in:Biochemical and biophysical research communications 1979-02, Vol.86 (4), p.1096-1101
Hauptverfasser: Farbiszewski, R., Wincewicz-Pietrzykowska, A., Bańkowski, E., Gabryel, H.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acids - analysis
Animals
Arginine - analysis
Cytosol - analysis
Isoelectric Focusing
Male
Neoplasm Proteins - analysis
Neoplasms, Experimental - analysis
Peptides - analysis
Rats
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Zusammenfassung:Arginine-rich peptide from cytosol of Guerin epitheliomas has been isolated and characterized. It contains 212.0 arginine residues, 77.1 lysine and 36.9 histidine residues per 1000 residues of amino acids. The ratio of basic to the acidic amino acids amounted to 1.23. The peptide has a cationic character with an isoelectric point of 8.6. No carbohydrate component was found in this peptide. It is suggested that this peptide originates from decomposition of arginine-rich basic protein stated previously in cytosol of this tumor.
ISSN:0006-291X
1090-2104
DOI:10.1016/0006-291X(79)90230-4