Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis

Hepatocyte growth factor (HGF) is a pleiotropic cytokine able to evoke a wide array of cellular responses including proliferation, migration, and survival through activation of its receptor c‐met. Various types of leukocytes have been described to express c‐met suggesting that HGF/c‐met signaling ma...

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Veröffentlicht in:	Glia 2010-04, Vol.58 (5), p.559-571
Hauptverfasser:	Moransard, Martijn, Sawitzky, Mandy, Fontana, Adriano, Suter, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - metabolism Bone Marrow Cells Cell Proliferation - drug effects Cells, Cultured Central Nervous System - pathology CNS inflammation Cytokines - genetics Cytokines - metabolism dendritic cells Dendritic Cells - drug effects Dendritic Cells - metabolism Disease Models, Animal Encephalomyelitis, Autoimmune, Experimental - chemically induced Encephalomyelitis, Autoimmune, Experimental - pathology Female Flow Cytometry Gene Expression Regulation - drug effects Gene Expression Regulation - physiology Glycoproteins Hepatocyte Growth Factor - genetics Hepatocyte Growth Factor - metabolism Hepatocyte Growth Factor - pharmacology Lipopolysaccharides - pharmacology Macrophages - metabolism Mice Mice, Inbred C57BL Mice, Knockout Microglia - physiology multiple sclerosis Myelin-Oligodendrocyte Glycoprotein Nitrates - metabolism oligodendrocyte progenitor Oligodendroglia - physiology Peptide Fragments Phagocytosis - physiology Proto-Oncogene Proteins c-met - genetics Proto-Oncogene Proteins c-met - metabolism Stem Cells Time Factors Tumor Necrosis Factor-alpha - deficiency
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