Environment, Mitochondria, and Parkinson's Disease

Parkinson's disease (PD) is a common and disabling neurodegenerative disease marked by progressive motor dysfunction, which results from selective degeneration of the nigrostriatal pathway. Epidemiological studies indicate that exposure to pesticides, rural living, farming, and drinking well wa...

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Veröffentlicht in:	The Neuroscientist (Baltimore, Md.) Md.), 2002-06, Vol.8 (3), p.192-197
Hauptverfasser:	Sherer, Todd B., Betarbet, Ranjita, Greenamyre, J. Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Electron Transport Complex I Environmental Exposure - adverse effects Humans Mitochondria - metabolism Mutation NADH, NADPH Oxidoreductases - metabolism Oxidative Stress Parkinson Disease - etiology Parkinson Disease - genetics Parkinson Disease - metabolism Parkinson Disease, Secondary - chemically induced Parkinson Disease, Secondary - metabolism Pesticides - adverse effects Risk Factors
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