Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man
This study was performed in order to establish whether endogenous opioids play a role in the inhibitory effect of melatonin on arginine-vasopressin (AVP) response to physical exercise. Seven healthy men underwent four bicycle ergometer tests until exhaustion [exercise control test, exercise plus nal...
Gespeichert in:
| Veröffentlicht in: | Regulatory peptides 2010-06, Vol.162 (1), p.1-4 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 4 |
|---|---|
| container_issue | 1 |
| container_start_page | 1 |
| container_title | Regulatory peptides |
| container_volume | 162 |
| creator | Coiro, Vittorio Volpi, Riccardo Maffei, Maria Ludovica Volta, Elio Melani, Andrea Chiodera, Paolo |
| description | This study was performed in order to establish whether endogenous opioids play a role in the inhibitory effect of melatonin on arginine-vasopressin (AVP) response to physical exercise. Seven healthy men underwent four bicycle ergometer tests until exhaustion [exercise control test, exercise plus naloxone (2
mg injected plus 5
mg infused intravenously), exercise plus melatonin (6
mg), exercise plus melatonin plus naloxone]. Plasma AVP concentrations, non endocrine physiological parameters (NEPP) and biochemical parameters were evaluated during all tests. NEPP and biochemical values had a similar pattern during all tests. Physical exercise significantly increased the AVP levels. The pre-treatment with melatonin inhibited the AVP response to physical exercise. In contrast, naloxone had no effect on AVP rise during exercise, when given alone, whereas it abolished the negative effect of melatonin on AVP response to physical exercise. Our data indicate that naloxone-sensitive endogenous opiates mediate the inhibitory modulation exerted by melatonin on the AVP response to physical exercise. |
| doi_str_mv | 10.1016/j.regpep.2010.03.007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_744707198</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0167011510000546</els_id><sourcerecordid>733959787</sourcerecordid><originalsourceid>FETCH-LOGICAL-c423t-5861f9b37d7b282ae6ead5e071228b040b2e33bdca31fd2483029cca5191d10c3</originalsourceid><addsrcrecordid>eNqFkc1u1DAURi0EosPAGyDkDeoqw7WdxM4GCVUtIFViA2vLsW86HiV2sDNVZ82L42GmZQcrS77n_ug7hLxlsGHA2g-7TcK7GecNh_IFYgMgn5EVU1JUrFXtc7IqmKyAseaCvMp5B8AaKcVLcsFB1G2nuhX5dT0MaBcaBxrMGB9iQBoDXbZIfdj63i8xHSg-QROOZonBh0cq4Ygm47Fm0p0vFazuTY5zwpwL5oPbW3S0P9B5e8jempHiAybr83EFnUx4TV4MZsz45vyuyY-b6-9XX6rbb5-_Xn26rWzNxVI1qmVD1wvpZM8VN9iicQ2CZJyrHmroOQrRO2sEGxyvlQDeWWsa1jHHwIo1uTzNnVP8uce86Mlni-NoAsZ91rKuZZnWqf-TQnRNJ0vUa1KfSJtizgkHPSc_mXTQDPTRk97pkyd99KRB6OKptL07L9j3E7qnpkcxBXh_BkwukQ3JhJLYX44raOs_-z-eOCzB3XtMOluPoSTuU1GmXfT_vuQ3tcu0Ug</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733959787</pqid></control><display><type>article</type><title>Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Coiro, Vittorio ; Volpi, Riccardo ; Maffei, Maria Ludovica ; Volta, Elio ; Melani, Andrea ; Chiodera, Paolo</creator><creatorcontrib>Coiro, Vittorio ; Volpi, Riccardo ; Maffei, Maria Ludovica ; Volta, Elio ; Melani, Andrea ; Chiodera, Paolo</creatorcontrib><description>This study was performed in order to establish whether endogenous opioids play a role in the inhibitory effect of melatonin on arginine-vasopressin (AVP) response to physical exercise. Seven healthy men underwent four bicycle ergometer tests until exhaustion [exercise control test, exercise plus naloxone (2
mg injected plus 5
mg infused intravenously), exercise plus melatonin (6
mg), exercise plus melatonin plus naloxone]. Plasma AVP concentrations, non endocrine physiological parameters (NEPP) and biochemical parameters were evaluated during all tests. NEPP and biochemical values had a similar pattern during all tests. Physical exercise significantly increased the AVP levels. The pre-treatment with melatonin inhibited the AVP response to physical exercise. In contrast, naloxone had no effect on AVP rise during exercise, when given alone, whereas it abolished the negative effect of melatonin on AVP response to physical exercise. Our data indicate that naloxone-sensitive endogenous opiates mediate the inhibitory modulation exerted by melatonin on the AVP response to physical exercise.</description><identifier>ISSN: 0167-0115</identifier><identifier>EISSN: 1873-1686</identifier><identifier>DOI: 10.1016/j.regpep.2010.03.007</identifier><identifier>PMID: 20346989</identifier><identifier>CODEN: REPPDY</identifier><language>eng</language><publisher>Kidlington: Elsevier B.V</publisher><subject>Arginine Vasopressin - blood ; Arginine-vasopressin ; Biological and medical sciences ; Drug Interactions ; Exercise ; Fundamental and applied biological sciences. Psychology ; Humans ; Male ; Melatonin ; Melatonin - pharmacology ; Naloxone ; Naloxone - pharmacology ; Physical exercise ; Radioimmunoassay ; Vertebrates: endocrinology</subject><ispartof>Regulatory peptides, 2010-06, Vol.162 (1), p.1-4</ispartof><rights>2010 Elsevier B.V.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-5861f9b37d7b282ae6ead5e071228b040b2e33bdca31fd2483029cca5191d10c3</citedby><cites>FETCH-LOGICAL-c423t-5861f9b37d7b282ae6ead5e071228b040b2e33bdca31fd2483029cca5191d10c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.regpep.2010.03.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22806487$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20346989$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Coiro, Vittorio</creatorcontrib><creatorcontrib>Volpi, Riccardo</creatorcontrib><creatorcontrib>Maffei, Maria Ludovica</creatorcontrib><creatorcontrib>Volta, Elio</creatorcontrib><creatorcontrib>Melani, Andrea</creatorcontrib><creatorcontrib>Chiodera, Paolo</creatorcontrib><title>Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man</title><title>Regulatory peptides</title><addtitle>Regul Pept</addtitle><description>This study was performed in order to establish whether endogenous opioids play a role in the inhibitory effect of melatonin on arginine-vasopressin (AVP) response to physical exercise. Seven healthy men underwent four bicycle ergometer tests until exhaustion [exercise control test, exercise plus naloxone (2
mg injected plus 5
mg infused intravenously), exercise plus melatonin (6
mg), exercise plus melatonin plus naloxone]. Plasma AVP concentrations, non endocrine physiological parameters (NEPP) and biochemical parameters were evaluated during all tests. NEPP and biochemical values had a similar pattern during all tests. Physical exercise significantly increased the AVP levels. The pre-treatment with melatonin inhibited the AVP response to physical exercise. In contrast, naloxone had no effect on AVP rise during exercise, when given alone, whereas it abolished the negative effect of melatonin on AVP response to physical exercise. Our data indicate that naloxone-sensitive endogenous opiates mediate the inhibitory modulation exerted by melatonin on the AVP response to physical exercise.</description><subject>Arginine Vasopressin - blood</subject><subject>Arginine-vasopressin</subject><subject>Biological and medical sciences</subject><subject>Drug Interactions</subject><subject>Exercise</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Male</subject><subject>Melatonin</subject><subject>Melatonin - pharmacology</subject><subject>Naloxone</subject><subject>Naloxone - pharmacology</subject><subject>Physical exercise</subject><subject>Radioimmunoassay</subject><subject>Vertebrates: endocrinology</subject><issn>0167-0115</issn><issn>1873-1686</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAURi0EosPAGyDkDeoqw7WdxM4GCVUtIFViA2vLsW86HiV2sDNVZ82L42GmZQcrS77n_ug7hLxlsGHA2g-7TcK7GecNh_IFYgMgn5EVU1JUrFXtc7IqmKyAseaCvMp5B8AaKcVLcsFB1G2nuhX5dT0MaBcaBxrMGB9iQBoDXbZIfdj63i8xHSg-QROOZonBh0cq4Ygm47Fm0p0vFazuTY5zwpwL5oPbW3S0P9B5e8jempHiAybr83EFnUx4TV4MZsz45vyuyY-b6-9XX6rbb5-_Xn26rWzNxVI1qmVD1wvpZM8VN9iicQ2CZJyrHmroOQrRO2sEGxyvlQDeWWsa1jHHwIo1uTzNnVP8uce86Mlni-NoAsZ91rKuZZnWqf-TQnRNJ0vUa1KfSJtizgkHPSc_mXTQDPTRk97pkyd99KRB6OKptL07L9j3E7qnpkcxBXh_BkwukQ3JhJLYX44raOs_-z-eOCzB3XtMOluPoSTuU1GmXfT_vuQ3tcu0Ug</recordid><startdate>20100608</startdate><enddate>20100608</enddate><creator>Coiro, Vittorio</creator><creator>Volpi, Riccardo</creator><creator>Maffei, Maria Ludovica</creator><creator>Volta, Elio</creator><creator>Melani, Andrea</creator><creator>Chiodera, Paolo</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TS</scope></search><sort><creationdate>20100608</creationdate><title>Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man</title><author>Coiro, Vittorio ; Volpi, Riccardo ; Maffei, Maria Ludovica ; Volta, Elio ; Melani, Andrea ; Chiodera, Paolo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-5861f9b37d7b282ae6ead5e071228b040b2e33bdca31fd2483029cca5191d10c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Arginine Vasopressin - blood</topic><topic>Arginine-vasopressin</topic><topic>Biological and medical sciences</topic><topic>Drug Interactions</topic><topic>Exercise</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Male</topic><topic>Melatonin</topic><topic>Melatonin - pharmacology</topic><topic>Naloxone</topic><topic>Naloxone - pharmacology</topic><topic>Physical exercise</topic><topic>Radioimmunoassay</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Coiro, Vittorio</creatorcontrib><creatorcontrib>Volpi, Riccardo</creatorcontrib><creatorcontrib>Maffei, Maria Ludovica</creatorcontrib><creatorcontrib>Volta, Elio</creatorcontrib><creatorcontrib>Melani, Andrea</creatorcontrib><creatorcontrib>Chiodera, Paolo</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Physical Education Index</collection><jtitle>Regulatory peptides</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Coiro, Vittorio</au><au>Volpi, Riccardo</au><au>Maffei, Maria Ludovica</au><au>Volta, Elio</au><au>Melani, Andrea</au><au>Chiodera, Paolo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man</atitle><jtitle>Regulatory peptides</jtitle><addtitle>Regul Pept</addtitle><date>2010-06-08</date><risdate>2010</risdate><volume>162</volume><issue>1</issue><spage>1</spage><epage>4</epage><pages>1-4</pages><issn>0167-0115</issn><eissn>1873-1686</eissn><coden>REPPDY</coden><abstract>This study was performed in order to establish whether endogenous opioids play a role in the inhibitory effect of melatonin on arginine-vasopressin (AVP) response to physical exercise. Seven healthy men underwent four bicycle ergometer tests until exhaustion [exercise control test, exercise plus naloxone (2
mg injected plus 5
mg infused intravenously), exercise plus melatonin (6
mg), exercise plus melatonin plus naloxone]. Plasma AVP concentrations, non endocrine physiological parameters (NEPP) and biochemical parameters were evaluated during all tests. NEPP and biochemical values had a similar pattern during all tests. Physical exercise significantly increased the AVP levels. The pre-treatment with melatonin inhibited the AVP response to physical exercise. In contrast, naloxone had no effect on AVP rise during exercise, when given alone, whereas it abolished the negative effect of melatonin on AVP response to physical exercise. Our data indicate that naloxone-sensitive endogenous opiates mediate the inhibitory modulation exerted by melatonin on the AVP response to physical exercise.</abstract><cop>Kidlington</cop><pub>Elsevier B.V</pub><pmid>20346989</pmid><doi>10.1016/j.regpep.2010.03.007</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0167-0115 |
| ispartof | Regulatory peptides, 2010-06, Vol.162 (1), p.1-4 |
| issn | 0167-0115 1873-1686 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_744707198 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Arginine Vasopressin - blood Arginine-vasopressin Biological and medical sciences Drug Interactions Exercise Fundamental and applied biological sciences. Psychology Humans Male Melatonin Melatonin - pharmacology Naloxone Naloxone - pharmacology Physical exercise Radioimmunoassay Vertebrates: endocrinology |
| title | Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-30T15%3A45%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20naloxone%20on%20the%20inhibitory%20effect%20of%20melatonin%20on%20the%20release%20of%20arginine-vasopressin%20induced%20by%20physical%20exercise%20in%20man&rft.jtitle=Regulatory%20peptides&rft.au=Coiro,%20Vittorio&rft.date=2010-06-08&rft.volume=162&rft.issue=1&rft.spage=1&rft.epage=4&rft.pages=1-4&rft.issn=0167-0115&rft.eissn=1873-1686&rft.coden=REPPDY&rft_id=info:doi/10.1016/j.regpep.2010.03.007&rft_dat=%3Cproquest_cross%3E733959787%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=733959787&rft_id=info:pmid/20346989&rft_els_id=S0167011510000546&rfr_iscdi=true |