Neonatal Handling Impairs Spatial Memory and Leads to Altered Nitric Oxide Production and DNA Breaks in A Sex Specific Manner

Early life events lead to behavioral and neurochemical changes in adulthood. The aim of this study is to verify the effects of neonatal handling on spatial memory, nitric oxide (NO) production, antioxidant enzymatic activities and DNA breaks in the hippocampus of male and female adult rats. Litters...

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Veröffentlicht in:	Neurochemical research 2010-07, Vol.35 (7), p.1083-1091
Hauptverfasser:	Noschang, Cristie Grazziotin, Krolow, Rachel, Fontella, Fernanda Urruth, Arcego, Danusa M., Diehl, Luísa Amália, Weis, Simone Nardin, Arteni, Nice S., Dalmaz, Carla
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Biomedicine Catalase - metabolism Cell Biology Comet Assay DNA Breaks Female Glutathione Peroxidase - metabolism Handling (Psychology) Hippocampus - metabolism Male Maze Learning Memory NADPH Dehydrogenase - metabolism Neurochemistry Neurology Neurosciences Nitric Oxide - biosynthesis Original Paper Rats Rats, Wistar Sex Factors Space Perception Superoxide Dismutase - metabolism
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