Frontal white matter abnormalities following chronic ketamine use: a diffusion tensor imaging study

Ketamine abuse has been shown to have a deleterious impact on brain function. However, the precise mechanisms of ketamine dependence-induced pathological change remain poorly understood. Although there is evidence for white matter changes in drug abuse, the presence of white matter abnormalities in...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2010-07, Vol.133 (7), p.2115-2122
Hauptverfasser:	Liao, Yanhui, Tang, Jinsong, Ma, Mingdong, Wu, Zhimei, Yang, Mei, Wang, Xuyi, Liu, Tieqiao, Chen, Xiaogang, Fletcher, Paul C., Hao, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences diffusion tensor imaging Diffusion Tensor Imaging - methods Female fractional anisotropy Frontal Lobe - drug effects Frontal Lobe - pathology frontal white matter Humans Injuries of the nervous system and the skull. Diseases due to physical agents Ketamine - administration & dosage Ketamine - adverse effects ketamine dependence Male Medical sciences Nerve Fibers, Myelinated - drug effects Nerve Fibers, Myelinated - pathology Neurology Substance-Related Disorders - pathology Traumas. Diseases due to physical agents voxel-based morphometry Young Adult
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