Carvedilol-induced elevation in cytosolic free Ca2+ level and apoptosis in SIRC corneal epithelial cells

The effect of the cardiovascular drug carvedilol on cytosolic free Ca2+ concentrations ([Ca 2+]i) and viability was examined in Statens Seruminstitut rabbit cornea (SIRC) corneal epithelial cells. [Ca2+]i and cell viability were measured using the fluorescent dyes fura-2 and 4-[3-[4-lodophenyl]-2-4(...

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Veröffentlicht in:	Human & experimental toxicology 2010-06, Vol.29 (6), p.477-487
Hauptverfasser:	Shieh, Pochuen, Lee, Chih-Hung, Ng Ling Yi, Jan, Chung-Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Calcium Cells Cornea Drug toxicity and drugs side effects treatment Drugs Medical sciences Pharmacology. Drug treatments Rabbits Toxicity Toxicity: eye
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