WSS45, a sulfated a-D-glucan, strongly interferes with Dengue 2 virus infection in vitro

Aim: To investigate the mode of action of WSS45, one sulfated derivative of an α-D-glucan from the Gastrodia elata BI, on the multiplication cycle of dengue virus serotype 2 (DV2), including initial infection and intracellular replication. Methods: Virus multiplication in BHK cells were monitored by...

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Veröffentlicht in:Acta pharmacologica Sinica 2010-05, Vol.31 (5), p.585-592
Hauptverfasser: Tong, Xian-kun, Qiu, Hong, Zhang, Xin, Shi, Li-ping, Wang, Gui-feng, Ji, Fei-hong, Ding, Hui-yong, Tang, Wei, Ding, Kan, Zuo, Jian-ping
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Sprache:eng
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