Mechanisms underlying striatal vulnerability to 3‐nitropropionic acid

J. Neurochem. (2010) 114, 597–605. The striatum is a cerebral structure particularly susceptible to the metabolic challenge exerted by 3‐nitropropionic acid (3‐NPA), a toxin that inhibits the respiratory chain at complex II. The striatum, which receives the nerve endings of the nigro‐striatal pathwa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 2010-07, Vol.114 (2), p.597-605
Hauptverfasser:	Herrera‐Mundo, Nieves, Sitges, María
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Animals Biological and medical sciences Brain Catecholamines - metabolism catechol‐O‐methyltransferase Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Corpus Striatum - drug effects Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dopamine - analogs & derivatives Dopamine - metabolism dopamine‐quinone‐adducts Exocytosis - drug effects Fundamental and applied biological sciences. Psychology In Vitro Techniques Male Medical sciences monoamine oxidase type A monoamine oxidase type B Motor Activity - drug effects Nerve Endings - metabolism Neurochemistry Neurology Neurotoxins - toxicity Nitro Compounds - toxicity Oxidative Stress - drug effects Propionates - toxicity Rats Rats, Wistar Reactive Oxygen Species - metabolism reactive‐oxygen‐species Synaptosomes - metabolism Toxins Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!