Pseudomonas fluorescens orchestrates a fine metabolic-balancing act to counter aluminium toxicity

Aluminium (Al), an environmental toxin, is known to disrupt cellular functions by perturbing iron (Fe) homeostasis. However, Fe is essential for such metabolic processes as the tricarboxylic acid (TCA) cycle and oxidative phosphorylation, the two pivotal networks that mediate ATP production during a...

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Veröffentlicht in:	Environmental microbiology 2010-06, Vol.12 (6), p.1384-1390
Hauptverfasser:	Lemire, Joseph, Mailloux, Ryan, Auger, Christopher, Whalen, Daniel, Appanna, Vasu D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Aluminum - toxicity Bacterial Proteins - chemistry Bacterial Proteins - metabolism Citric Acid - metabolism Citric Acid Cycle - physiology Electron Transport - physiology Homeostasis Intramolecular Oxidoreductases - metabolism Iron - metabolism Iron-Sulfur Proteins - metabolism Isocitrate Dehydrogenase - metabolism Isocitrate Lyase - metabolism NAD - metabolism Pseudomonas fluorescens Pseudomonas fluorescens - drug effects Pseudomonas fluorescens - metabolism Succinate-CoA Ligases - metabolism
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