Sensitive Method For Detection Of Cocaine And Associated Analytes By Liquid Chromatography-Tandem Mass Spectrometry In Urine

Cocaine (COC) is a potent CNS stimulant that is metabolized to benzoylecgonine (BE) and further metabolized to minor metabolites such as m-hydroxybenzoylecgonine (m-HOBE). COC is also metabolized to norcocaine (NC). Cocaethylene (CE) is formed when cocaine and ethyl alcohol are used simultaneously....

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Veröffentlicht in:	Journal of analytical toxicology 2009-10, Vol.33 (8), p.447-455
Hauptverfasser:	Langman, Loralie J., Bjergum, Matthew W., Williamson, Christopher L., Crow, Frank W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography, High Pressure Liquid Cocaine - analogs & derivatives Cocaine - urine Cocaine-Related Disorders - diagnosis Cocaine-Related Disorders - urine Dopamine Uptake Inhibitors - urine Ethanol - blood Gas Chromatography-Mass Spectrometry Humans Reproducibility of Results Solid Phase Extraction Spectrometry, Mass, Electrospray Ionization Substance Abuse Detection - methods Tandem Mass Spectrometry
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