Applying small RNA molecules to the directed treatment of human diseases: realizing the potential

Small interfering RNAs (siRNA) and microRNAs (miRNA) are gaining considerable attention in the pharmaceutical and biotechnology industries, as research has revealed their likely clinical and agricultural applications. The capacity of siRNAs to dramatically and specifically reduce the expression of t...

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Veröffentlicht in:	Expert opinion on therapeutic targets 2008-01, Vol.12 (1), p.115-127
Hauptverfasser:	Pappas, Todd C, Bader, Andreas G, Andruss, Bernard F, Brown, David, Ford, Lance P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Clinical Trials as Topic - trends delivery Gene Silencing - physiology Gene Targeting - trends Humans microRNA MicroRNAs - antagonists & inhibitors MicroRNAs - biosynthesis MicroRNAs - metabolism RNA drugs RNA, Small Interfering - biosynthesis RNA, Small Interfering - genetics RNA, Small Interfering - therapeutic use small interfering RNA therapeutics
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