Biological activities of cytokine-neutralizing hyaluronic acid-antibody conjugates

ABSTRACT Wound healing represents a highly regulated, orchestrated response of cells recruited to sites of injury. High molecular weight hyaluronic acid was conjugated with monoclonal antibodies to the cytokine interleukin‐1β to create a matrix‐forming polymer capable of modifying healing. Using gel...

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Veröffentlicht in:	Wound repair and regeneration 2010-05, Vol.18 (3), p.302-310
Hauptverfasser:	Sun, Liang Tso, Bencherif, Sidi A., Gilbert, Thomas W., Farkas, Adam M., Lotze, Michael T., Washburn, Newell R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antibodies, Neutralizing - immunology Cell Line, Tumor Extracellular Matrix - immunology Humans Hyaluronic Acid - immunology Immunoconjugates In Vitro Techniques Inflammation - immunology Interleukin-1beta - immunology Monocytes Rats Rats, Sprague-Dawley Tumor Necrosis Factor-alpha - immunology Wound Healing - immunology
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